| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
135 genes differentially expressed following the BRD-K33379087_tivantinib_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADIRF | adipogenesis regulatory factor |
| AHI1 | Abelson helper integration site 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APOD | apolipoprotein D |
| AURKA | aurora kinase A |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCDC109B | coiled-coil domain containing 109B |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CP | ceruloplasmin (ferroxidase) |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHCR24 | 24-dehydrocholesterol reductase |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| FAM46A | family with sequence similarity 46, member A |
| FOSL1 | FOS-like antigen 1 |
| FST | follistatin |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HP | haptoglobin |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| IRS1 | insulin receptor substrate 1 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KIF14 | kinesin family member 14 |
| KIF20A | kinesin family member 20A |
| KLK10 | kallikrein-related peptidase 10 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT18 | keratin 18, type I |
| KYNU | kynureninase |
| LTF | lactotransferrin |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1M | metallothionein 1M |
| NELL2 | NEL-like 2 (chicken) |
| NTS | neurotensin |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDZD8 | PDZ domain containing 8 |
| PODXL | podocalyxin-like |
| RAB31 | RAB31, member RAS oncogene family |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A12 | S100 calcium binding protein A12 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SNX10 | sorting nexin 10 |
| SYNJ2 | synaptojanin 2 |
| TPBG | trophoblast glycoprotein |
| TRIB2 | tribbles pseudokinase 2 |
| UROD | uroporphyrinogen decarboxylase |
| USP22 | ubiquitin specific peptidase 22 |
| VDAC1 | voltage-dependent anion channel 1 |
| VSNL1 | visinin-like 1 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| CD24 | CD24 molecule |
| CDK1 | cyclin-dependent kinase 1 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTSZ | cathepsin Z |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DCN | decorin |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| DUSP6 | dual specificity phosphatase 6 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| F12 | coagulation factor XII (Hageman factor) |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GNAS | GNAS complex locus |
| GPX3 | glutathione peroxidase 3 |
| HBB | hemoglobin, beta |
| HES1 | hes family bHLH transcription factor 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA1A | heat shock 70kDa protein 1A |
| IFI44L | interferon-induced protein 44-like |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KIAA0101 | KIAA0101 |
| KRT19 | keratin 19, type I |
| MELK | maternal embryonic leucine zipper kinase |
| MSH6 | mutS homolog 6 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MXI1 | MAX interactor 1, dimerization protein |
| NET1 | neuroepithelial cell transforming 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PEG10 | paternally expressed 10 |
| PRKCD | protein kinase C, delta |
| PSPH | phosphoserine phosphatase |
| RAB2A | RAB2A, member RAS oncogene family |
| RGS2 | regulator of G-protein signaling 2 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RRM2 | ribonucleotide reductase M2 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TNS3 | tensin 3 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPD52 | tumor protein D52 |
| TRIB1 | tribbles pseudokinase 1 |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VCAM1 | vascular cell adhesion molecule 1 |
| VIM | vimentin |
| WEE1 | WEE1 G2 checkpoint kinase |
| XIST | X inactive specific transcript (non-protein coding) |
