BRD-K34533029_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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35 genes differentially expressed following the BRD-K34533029_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BEX1 brain expressed, X-linked 1
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CHGB chromogranin B
DUOX2 dual oxidase 2
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GRIA2 glutamate receptor, ionotropic, AMPA 2
HMOX1 heme oxygenase 1
LAPTM4B lysosomal protein transmembrane 4 beta
MAP7 microtubule-associated protein 7
NAMPT nicotinamide phosphoribosyltransferase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDIA3 protein disulfide isomerase family A, member 3
RHOBTB3 Rho-related BTB domain containing 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SPRED2 sprouty-related, EVH1 domain containing 2
SQSTM1 sequestosome 1
TIMP4 TIMP metallopeptidase inhibitor 4
TSKU tsukushi, small leucine rich proteoglycan
WASF3 WAS protein family, member 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CALML4 calmodulin-like 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HIST1H1C histone cluster 1, H1c
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KDM5D lysine (K)-specific demethylase 5D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NR2F2 nuclear receptor subfamily 2, group F, member 2
RPS4Y1 ribosomal protein S4, Y-linked 1
TCTA T-cell leukemia translocation altered
TPPP3 tubulin polymerization-promoting protein family member 3
TXNIP thioredoxin interacting protein