BRD-K34711351_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K34711351_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD52 CD52 molecule
CELF2 CUGBP, Elav-like family member 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC4 chloride intracellular channel 4
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DCN decorin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GAB2 GRB2-associated binding protein 2
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGKV4-1 immunoglobulin kappa variable 4-1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KRT14 keratin 14, type I
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MT1M metallothionein 1M
OPN3 opsin 3
PIR pirin (iron-binding nuclear protein)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PTN pleiotrophin
RGCC regulator of cell cycle
SRGN serglycin
STS steroid sulfatase (microsomal), isozyme S
TARP TCR gamma alternate reading frame protein
TTN titin

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ASPH aspartate beta-hydroxylase
CCND1 cyclin D1
CCNF cyclin F
CD59 CD59 molecule, complement regulatory protein
CD9 CD9 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CLDN3 claudin 3
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
F3 coagulation factor III (thromboplastin, tissue factor)
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
IRS1 insulin receptor substrate 1
KRT7 keratin 7, type II
LOC100505650 uncharacterized LOC100505650
MET MET proto-oncogene, receptor tyrosine kinase
MXRA7 matrix-remodelling associated 7
MYOF myoferlin
OAT ornithine aminotransferase
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PROM1 prominin 1
PSPH phosphoserine phosphatase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOX11 SRY (sex determining region Y)-box 11
SRSF6 serine/arginine-rich splicing factor 6
TFPI2 tissue factor pathway inhibitor 2
TMEM47 transmembrane protein 47
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble