BRD-K35024477_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K35024477_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
BDKRB2 bradykinin receptor B2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA2 carbonic anhydrase II
CCL20 chemokine (C-C motif) ligand 20
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GDF15 growth differentiation factor 15
GUSBP11 glucuronidase, beta pseudogene 11
HK2 hexokinase 2
LUM lumican
MAGEA3 melanoma antigen family A3
MAN1A1 mannosidase, alpha, class 1A, member 1
MMD monocyte to macrophage differentiation-associated
PCSK1 proprotein convertase subtilisin/kexin type 1
PLIN2 perilipin 2
QPCT glutaminyl-peptide cyclotransferase
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
WSB1 WD repeat and SOCS box containing 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
BAD BCL2-associated agonist of cell death
CENPE centromere protein E, 312kDa
GNAS GNAS complex locus
KRT6A keratin 6A, type II
NRCAM neuronal cell adhesion molecule
S100A2 S100 calcium binding protein A2
SATB1 SATB homeobox 1
SOX11 SRY (sex determining region Y)-box 11
SPON1 spondin 1, extracellular matrix protein
SPTBN1 spectrin, beta, non-erythrocytic 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3