BRD-K35133769_-666_A375_6.0_h_10.0_um Gene Set
Genes
48 genes differentially expressed following the BRD-K35133769_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
AUTS2
|
autism susceptibility candidate 2
|
|
COL11A1
|
collagen, type XI, alpha 1
|
|
FBLN1
|
fibulin 1
|
|
GLUL
|
glutamate-ammonia ligase
|
|
GPRC5B
|
G protein-coupled receptor, class C, group 5, member B
|
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1
|
|
LMO3
|
LIM domain only 3 (rhombotin-like 2)
|
|
MYH11
|
myosin, heavy chain 11, smooth muscle
|
|
PTK2
|
protein tyrosine kinase 2
|
|
S100A8
|
S100 calcium binding protein A8
|
|
S100A9
|
S100 calcium binding protein A9
|
|
SH3BGRL
|
SH3 domain binding glutamate-rich protein like
|
|
SORBS2
|
sorbin and SH3 domain containing 2
|
|
SULF1
|
sulfatase 1
|
|
SYT1
|
synaptotagmin I
|
|
TPD52L1
|
tumor protein D52-like 1
|
|
TRIM2
|
tripartite motif containing 2
|
|
TRIM22
|
tripartite motif containing 22
|
|
UBQLN2
|
ubiquilin 2
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ADGRG2
|
adhesion G protein-coupled receptor G2
|
|
AKR1B10
|
aldo-keto reductase family 1, member B10 (aldose reductase)
|
|
ALCAM
|
activated leukocyte cell adhesion molecule
|
|
ALDH1A3
|
aldehyde dehydrogenase 1 family, member A3
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
DDX17
|
DEAD (Asp-Glu-Ala-Asp) box helicase 17
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
|
EFNB2
|
ephrin-B2
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
|
KRT14
|
keratin 14, type I
|
|
KRT17
|
keratin 17, type I
|
|
LAMP1
|
lysosomal-associated membrane protein 1
|
|
MIA
|
melanoma inhibitory activity
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
|
NOLC1
|
nucleolar and coiled-body phosphoprotein 1
|
|
PXDN
|
peroxidasin
|
|
SERPINB5
|
serpin peptidase inhibitor, clade B (ovalbumin), member 5
|
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
|
TFF1
|
trefoil factor 1
|
|
TFF3
|
trefoil factor 3 (intestinal)
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TMEM2
|
transmembrane protein 2
|
|
TNPO1
|
transportin 1
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
|
TSPAN3
|
tetraspanin 3
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
