BRD-K35133769_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the BRD-K35133769_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
COL11A1 collagen, type XI, alpha 1
FBLN1 fibulin 1
GLUL glutamate-ammonia ligase
GPRC5B G protein-coupled receptor, class C, group 5, member B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MYH11 myosin, heavy chain 11, smooth muscle
PTK2 protein tyrosine kinase 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SH3BGRL SH3 domain binding glutamate-rich protein like
SORBS2 sorbin and SH3 domain containing 2
SULF1 sulfatase 1
SYT1 synaptotagmin I
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
UBQLN2 ubiquilin 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFNB2 ephrin-B2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LAMP1 lysosomal-associated membrane protein 1
MIA melanoma inhibitory activity
MRPS16 mitochondrial ribosomal protein S16
NOLC1 nucleolar and coiled-body phosphoprotein 1
PXDN peroxidasin
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TNPO1 transportin 1
TRAPPC3 trafficking protein particle complex 3
TSPAN3 tetraspanin 3
UBE2A ubiquitin-conjugating enzyme E2A