BRD-K35573744_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

41 genes differentially expressed following the BRD-K35573744_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOB apolipoprotein B
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
CHN1 chimerin 1
CPE carboxypeptidase E
CYR61 cysteine-rich, angiogenic inducer, 61
DIO1 deiodinase, iodothyronine, type I
FRY furry homolog (Drosophila)
HAL histidine ammonia-lyase
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
JUN jun proto-oncogene
KRT19 keratin 19, type I
METTL7A methyltransferase like 7A
MSLN mesothelin
MT1F metallothionein 1F
MT1M metallothionein 1M
MYC v-myc avian myelocytomatosis viral oncogene homolog
NELL2 NEL-like 2 (chicken)
RFC5 replication factor C (activator 1) 5, 36.5kDa
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TP53BP2 tumor protein p53 binding protein 2
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ACTB actin, beta
CD24 CD24 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
ERBB3 erb-b2 receptor tyrosine kinase 3
IER3 immediate early response 3
IFITM2 interferon induced transmembrane protein 2
NRIP1 nuclear receptor interacting protein 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
SOX9 SRY (sex determining region Y)-box 9
UBE3B ubiquitin protein ligase E3B
XPO7 exportin 7