BRD-K35716340_-666_A375_6.0_h_12.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K35716340_-666_A375_6.0_h_12.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGAP29 Rho GTPase activating protein 29
C3 complement component 3
CCND2 cyclin D2
CHN1 chimerin 1
COL13A1 collagen, type XIII, alpha 1
CYR61 cysteine-rich, angiogenic inducer, 61
PDE4B phosphodiesterase 4B, cAMP-specific
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TMEM123 transmembrane protein 123

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
EBP emopamil binding protein (sterol isomerase)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM46A family with sequence similarity 46, member A
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
LPL lipoprotein lipase
LTBP3 latent transforming growth factor beta binding protein 3
MCUR1 mitochondrial calcium uniporter regulator 1
QDPR quinoid dihydropteridine reductase
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TMEM2 transmembrane protein 2
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3