BRD-K35920785_2-(4-(2-chlorophenylamino)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-ylamino)ethanol wh-gc-round5-01_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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68 genes differentially expressed following the BRD-K35920785_2-(4-(2-chlorophenylamino)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-ylamino)ethanol wh-gc-round5-01_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AHCYL1 adenosylhomocysteinase-like 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARG1 arginase 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
C7 complement component 7
CCL19 chemokine (C-C motif) ligand 19
CHRDL1 chordin-like 1
COL15A1 collagen, type XV, alpha 1
CTSH cathepsin H
CXCL9 chemokine (C-X-C motif) ligand 9
DHRS2 dehydrogenase/reductase (SDR family) member 2
DMD dystrophin
DPT dermatopontin
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPS8 epidermal growth factor receptor pathway substrate 8
FAM46A family with sequence similarity 46, member A
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
HOPX HOP homeobox
MAOA monoamine oxidase A
MTSS1 metastasis suppressor 1
OAT ornithine aminotransferase
PCP4 Purkinje cell protein 4
PLS3 plastin 3
RELN reelin
SLIT2 slit homolog 2 (Drosophila)
SPTSSA serine palmitoyltransferase, small subunit A
TBL1X transducin (beta)-like 1X-linked
TKTL1 transketolase-like 1
TP63 tumor protein p63

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
BID BH3 interacting domain death agonist
BMP7 bone morphogenetic protein 7
CD1E CD1e molecule
CLU clusterin
CRIP1 cysteine-rich protein 1 (intestinal)
CTSZ cathepsin Z
CXCL5 chemokine (C-X-C motif) ligand 5
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLIPR1 GLI pathogenesis-related 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIST1H4C histone cluster 1, H4c
KRT18 keratin 18, type I
LXN latexin
MICB MHC class I polypeptide-related sequence B
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PDLIM5 PDZ and LIM domain 5
PLAC8 placenta-specific 8
PNMAL1 paraneoplastic Ma antigen family-like 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKCA protein kinase C, alpha
PTX3 pentraxin 3, long
PXDN peroxidasin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBM34 RNA binding motif protein 34
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SORBS3 sorbin and SH3 domain containing 3
STC2 stanniocalcin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble