BRD-K36022244_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K36022244_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA2 carbonic anhydrase II
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CHGB chromogranin B
CHMP4A charged multivesicular body protein 4A
CXCL14 chemokine (C-X-C motif) ligand 14
FGFR2 fibroblast growth factor receptor 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP5 insulin-like growth factor binding protein 5
LDOC1 leucine zipper, down-regulated in cancer 1
NARFL nuclear prelamin A recognition factor-like
NEBL nebulette
NT5E 5'-nucleotidase, ecto (CD73)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRUNE2 prune homolog 2 (Drosophila)
QPCT glutaminyl-peptide cyclotransferase
RAI14 retinoic acid induced 14
RGCC regulator of cell cycle
SCGB1D2 secretoglobin, family 1D, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
TOB1 transducer of ERBB2, 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CELF2 CUGBP, Elav-like family member 2
EGFR epidermal growth factor receptor
EHBP1 EH domain binding protein 1
FAM129A family with sequence similarity 129, member A
HOXA5 homeobox A5
HP haptoglobin
IFI16 interferon, gamma-inducible protein 16
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
LAMA4 laminin, alpha 4
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAPTM4B lysosomal protein transmembrane 4 beta
NRIP1 nuclear receptor interacting protein 1
OXTR oxytocin receptor
RBP1 retinol binding protein 1, cellular
SATB1 SATB homeobox 1
SLA Src-like-adaptor
SPATS2L spermatogenesis associated, serine-rich 2-like
Funding