Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-K36363294_I-BET151_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
ASMTL | acetylserotonin O-methyltransferase-like |
CCDC85B | coiled-coil domain containing 85B |
CCDC92 | coiled-coil domain containing 92 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CPNE3 | copine III |
CTSB | cathepsin B |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DUSP10 | dual specificity phosphatase 10 |
EDNRB | endothelin receptor type B |
EFNB2 | ephrin-B2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
FAM50A | family with sequence similarity 50, member A |
FUCA1 | fucosidase, alpha-L- 1, tissue |
FZD7 | frizzled class receptor 7 |
GOLGA8H | golgin A8 family, member H |
GPNMB | glycoprotein (transmembrane) nmb |
GPX1 | glutathione peroxidase 1 |
GRN | granulin |
GSN | gelsolin |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BK | histone cluster 1, H2bk |
HOOK2 | hook microtubule-tethering protein 2 |
HSPA1A | heat shock 70kDa protein 1A |
INSIG1 | insulin induced gene 1 |
IQGAP1 | IQ motif containing GTPase activating protein 1 |
JAG1 | jagged 1 |
KAZN | kazrin, periplakin interacting protein |
KDM5D | lysine (K)-specific demethylase 5D |
KRT5 | keratin 5, type II |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LGMN | legumain |
MACF1 | microtubule-actin crosslinking factor 1 |
MAST2 | microtubule associated serine/threonine kinase 2 |
MTSS1 | metastasis suppressor 1 |
MVP | major vault protein |
MXRA7 | matrix-remodelling associated 7 |
MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase |
MYLK | myosin light chain kinase |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEU1 | sialidase 1 (lysosomal sialidase) |
NOTCH2NL | notch 2 N-terminal like |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PALLD | palladin, cytoskeletal associated protein |
PNKP | polynucleotide kinase 3'-phosphatase |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SCAND1 | SCAN domain containing 1 |
SCPEP1 | serine carboxypeptidase 1 |
SIRT3 | sirtuin 3 |
SLC16A6 | solute carrier family 16, member 6 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SQSTM1 | sequestosome 1 |
STXBP1 | syntaxin binding protein 1 |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
TANK | TRAF family member-associated NFKB activator |
TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TM7SF2 | transmembrane 7 superfamily member 2 |
TMEM2 | transmembrane protein 2 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPP1 | tripeptidyl peptidase I |
TUBA1A | tubulin, alpha 1a |
TXNIP | thioredoxin interacting protein |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
Symbol | Name |
---|---|
ADGRG1 | adhesion G protein-coupled receptor G1 |
ANXA1 | annexin A1 |
AQP3 | aquaporin 3 (Gill blood group) |
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
BCHE | butyrylcholinesterase |
CALB1 | calbindin 1, 28kDa |
CCDC86 | coiled-coil domain containing 86 |
CRYZ | crystallin, zeta (quinone reductase) |
DPH2 | DPH2 homolog (S. cerevisiae) |
DUSP2 | dual specificity phosphatase 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FAM129A | family with sequence similarity 129, member A |
FSCN1 | fascin actin-bundling protein 1 |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IARS | isoleucyl-tRNA synthetase |
IFRD2 | interferon-related developmental regulator 2 |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
IPO5 | importin 5 |
JADE2 | jade family PHD finger 2 |
MAL | mal, T-cell differentiation protein |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
MRPL3 | mitochondrial ribosomal protein L3 |
MSH6 | mutS homolog 6 |
MSLN | mesothelin |
MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
NMI | N-myc (and STAT) interactor |
NOP16 | NOP16 nucleolar protein |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
P3H2 | prolyl 3-hydroxylase 2 |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PDLIM1 | PDZ and LIM domain 1 |
PFKP | phosphofructokinase, platelet |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PLBD1 | phospholipase B domain containing 1 |
PXMP2 | peroxisomal membrane protein 2, 22kDa |
PYCR1 | pyrroline-5-carboxylate reductase 1 |
RPP40 | ribonuclease P/MRP 40kDa subunit |
SET | SET nuclear proto-oncogene |
SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
SLC35F2 | solute carrier family 35, member F2 |
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SRM | spermidine synthase |
SRP72 | signal recognition particle 72kDa |
STEAP3 | STEAP family member 3, metalloreductase |
TAGLN2 | transgelin 2 |
TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
TRBC1 | T cell receptor beta constant 1 |
TRIM14 | tripartite motif containing 14 |
TSPAN8 | tetraspanin 8 |
XIST | X inactive specific transcript (non-protein coding) |