Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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70 genes differentially expressed following the BRD-K36740062_GSK-1070916_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ATF3 | activating transcription factor 3 |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
BASP1 | brain abundant, membrane attached signal protein 1 |
BTG2 | BTG family, member 2 |
CCND2 | cyclin D2 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CES2 | carboxylesterase 2 |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
EGR1 | early growth response 1 |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
FDXR | ferredoxin reductase |
GAS6 | growth arrest-specific 6 |
GDF15 | growth differentiation factor 15 |
GREM1 | gremlin 1, DAN family BMP antagonist |
H2BFS | H2B histone family, member S (pseudogene) |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BE | histone cluster 1, H2be |
HIST1H2BK | histone cluster 1, H2bk |
KLK11 | kallikrein-related peptidase 11 |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
ODC1 | ornithine decarboxylase 1 |
POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
RPS27L | ribosomal protein S27-like |
SESN1 | sestrin 1 |
SQSTM1 | sequestosome 1 |
TIGAR | TP53 induced glycolysis regulatory phosphatase |
TOB1 | transducer of ERBB2, 1 |
TRIM22 | tripartite motif containing 22 |
WDTC1 | WD and tetratricopeptide repeats 1 |
ZMAT3 | zinc finger, matrin-type 3 |
Symbol | Name |
---|---|
ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
BACE2 | beta-site APP-cleaving enzyme 2 |
BRCA1 | breast cancer 1, early onset |
C10ORF10 | chromosome 10 open reading frame 10 |
C3 | complement component 3 |
CDC25A | cell division cycle 25A |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
EPHA3 | EPH receptor A3 |
GLUL | glutamate-ammonia ligase |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
JADE2 | jade family PHD finger 2 |
KRT23 | keratin 23, type I |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
LTF | lactotransferrin |
LYZ | lysozyme |
NES | nestin |
PRDX2 | peroxiredoxin 2 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SORBS3 | sorbin and SH3 domain containing 3 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEM45A | transmembrane protein 45A |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TPM1 | tropomyosin 1 (alpha) |
TSPAN13 | tetraspanin 13 |