Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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82 genes differentially expressed following the BRD-K36740062_GSK-1070916_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABAT | 4-aminobutyrate aminotransferase |
ACKR3 | atypical chemokine receptor 3 |
AGR2 | anterior gradient 2 |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
AREG | amphiregulin |
BASP1 | brain abundant, membrane attached signal protein 1 |
BTG2 | BTG family, member 2 |
C14ORF132 | chromosome 14 open reading frame 132 |
CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CELF2 | CUGBP, Elav-like family member 2 |
CST1 | cystatin SN |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DDIT4 | DNA-damage-inducible transcript 4 |
FXYD3 | FXYD domain containing ion transport regulator 3 |
GATA3 | GATA binding protein 3 |
GDF15 | growth differentiation factor 15 |
GSPT2 | G1 to S phase transition 2 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
H2BFS | H2B histone family, member S (pseudogene) |
HEPH | hephaestin |
HIST1H1C | histone cluster 1, H1c |
HIST1H3H | histone cluster 1, H3h |
HIST2H2BE | histone cluster 2, H2be |
IGF1R | insulin-like growth factor 1 receptor |
MAMLD1 | mastermind-like domain containing 1 |
MSRB2 | methionine sulfoxide reductase B2 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PLAT | plasminogen activator, tissue |
RGS5 | regulator of G-protein signaling 5 |
RPS11 | ribosomal protein S11 |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SESN1 | sestrin 1 |
SMAD3 | SMAD family member 3 |
SVIL | supervillin |
TCEAL4 | transcription elongation factor A (SII)-like 4 |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
THBS1 | thrombospondin 1 |
TLR4 | toll-like receptor 4 |
TPD52L1 | tumor protein D52-like 1 |
TRIM22 | tripartite motif containing 22 |
ZMAT3 | zinc finger, matrin-type 3 |
ZMYM2 | zinc finger, MYM-type 2 |
Symbol | Name |
---|---|
ATAD2 | ATPase family, AAA domain containing 2 |
BIRC5 | baculoviral IAP repeat containing 5 |
CA2 | carbonic anhydrase II |
CADM1 | cell adhesion molecule 1 |
CALR | calreticulin |
CCNB2 | cyclin B2 |
CCNE2 | cyclin E2 |
CDC20 | cell division cycle 20 |
CDC25A | cell division cycle 25A |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CLEC11A | C-type lectin domain family 11, member A |
COPS7A | COP9 signalosome subunit 7A |
DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FOXM1 | forkhead box M1 |
GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GPNMB | glycoprotein (transmembrane) nmb |
GRWD1 | glutamate-rich WD repeat containing 1 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
KIF14 | kinesin family member 14 |
KIF20A | kinesin family member 20A |
LTF | lactotransferrin |
MMP9 | matrix metallopeptidase 9 |
MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
MT1E | metallothionein 1E |
NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
PLK1 | polo-like kinase 1 |
PTN | pleiotrophin |
RGS1 | regulator of G-protein signaling 1 |
SHCBP1 | SHC SH2-domain binding protein 1 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
UBE2S | ubiquitin-conjugating enzyme E2S |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |