BRD-K36740062_GSK-1070916_PC3_24_h_0.04_um Gene Set
Genes
64 genes differentially expressed following the BRD-K36740062_GSK-1070916_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ACLY
|
ATP citrate lyase
|
|
AREG
|
amphiregulin
|
|
BCL2A1
|
BCL2-related protein A1
|
|
BTG3
|
BTG family, member 3
|
|
CA2
|
carbonic anhydrase II
|
|
CD24
|
CD24 molecule
|
|
COL4A2
|
collagen, type IV, alpha 2
|
|
CYP1A1
|
cytochrome P450, family 1, subfamily A, polypeptide 1
|
|
ENO1
|
enolase 1, (alpha)
|
|
FBXO11
|
F-box protein 11
|
|
GRN
|
granulin
|
|
HPGD
|
hydroxyprostaglandin dehydrogenase 15-(NAD)
|
|
KRT8
|
keratin 8, type II
|
|
LMCD1
|
LIM and cysteine-rich domains 1
|
|
MAMLD1
|
mastermind-like domain containing 1
|
|
MT1M
|
metallothionein 1M
|
|
NEDD9
|
neural precursor cell expressed, developmentally down-regulated 9
|
|
NOV
|
nephroblastoma overexpressed
|
|
NPR3
|
natriuretic peptide receptor 3
|
|
OXTR
|
oxytocin receptor
|
|
PELO
|
pelota homolog (Drosophila)
|
|
PKM
|
pyruvate kinase, muscle
|
|
PRAME
|
preferentially expressed antigen in melanoma
|
|
PSAP
|
prosaposin
|
|
PTGER4
|
prostaglandin E receptor 4 (subtype EP4)
|
|
RTN2
|
reticulon 2
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
|
SLC12A2
|
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
|
|
SLC6A8
|
solute carrier family 6 (neurotransmitter transporter), member 8
|
|
TFF1
|
trefoil factor 1
|
|
TFF3
|
trefoil factor 3 (intestinal)
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
decreased expression
| Symbol |
Name |
|
ABLIM1
|
actin binding LIM protein 1
|
|
AKR1B10
|
aldo-keto reductase family 1, member B10 (aldose reductase)
|
|
ASPH
|
aspartate beta-hydroxylase
|
|
AUTS2
|
autism susceptibility candidate 2
|
|
BCL2
|
B-cell CLL/lymphoma 2
|
|
C3
|
complement component 3
|
|
COL1A2
|
collagen, type I, alpha 2
|
|
CPVL
|
carboxypeptidase, vitellogenic-like
|
|
CTSH
|
cathepsin H
|
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1
|
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
|
FABP4
|
fatty acid binding protein 4, adipocyte
|
|
FGG
|
fibrinogen gamma chain
|
|
G0S2
|
G0/G1 switch 2
|
|
GNAQ
|
guanine nucleotide binding protein (G protein), q polypeptide
|
|
GNG11
|
guanine nucleotide binding protein (G protein), gamma 11
|
|
HACD2
|
3-hydroxyacyl-CoA dehydratase 2
|
|
HOPX
|
HOP homeobox
|
|
HP
|
haptoglobin
|
|
IDH2
|
isocitrate dehydrogenase 2 (NADP+), mitochondrial
|
|
IGLL1
|
immunoglobulin lambda-like polypeptide 1
|
|
LMO3
|
LIM domain only 3 (rhombotin-like 2)
|
|
PIH1D1
|
PIH1 domain containing 1
|
|
RARRES1
|
retinoic acid receptor responder (tazarotene induced) 1
|
|
RGS4
|
regulator of G-protein signaling 4
|
|
SLPI
|
secretory leukocyte peptidase inhibitor
|
|
TACC2
|
transforming, acidic coiled-coil containing protein 2
|
|
TCF4
|
transcription factor 4
|
|
TOMM70A
|
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
|
|
TRIB2
|
tribbles pseudokinase 2
|
|
TSPAN5
|
tetraspanin 5
|
