BRD-K37043259_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K37043259_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK5 adenylate kinase 5
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
ANXA2P2 annexin A2 pseudogene 2
ARHGAP29 Rho GTPase activating protein 29
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRABP2 cellular retinoic acid binding protein 2
CSRP1 cysteine and glycine-rich protein 1
CXADR coxsackie virus and adenovirus receptor
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5A cytochrome b5 type A (microsomal)
CYTL1 cytokine-like 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EMP1 epithelial membrane protein 1
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FKBP1B FK506 binding protein 1B, 12.6 kDa
GAS7 growth arrest-specific 7
GDF15 growth differentiation factor 15
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB7 growth factor receptor-bound protein 7
H1F0 H1 histone family, member 0
HEBP1 heme binding protein 1
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFITM2 interferon induced transmembrane protein 2
IL17RB interleukin 17 receptor B
IL1B interleukin 1, beta
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
LIF leukemia inhibitory factor
LIMCH1 LIM and calponin homology domains 1
MBNL2 muscleblind-like splicing regulator 2
MTSS1 metastasis suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEFL neurofilament, light polypeptide
PALLD palladin, cytoskeletal associated protein
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PLAU plasminogen activator, urokinase
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRR7 proline rich 7 (synaptic)
PRSS3 protease, serine, 3
RGCC regulator of cell cycle
RHOB ras homolog family member B
S100A4 S100 calcium binding protein A4
SCGB1D2 secretoglobin, family 1D, member 2
SDC4 syndecan 4
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SRI sorcin
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM230 transmembrane protein 230
TMEM45A transmembrane protein 45A
TP53I3 tumor protein p53 inducible protein 3
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
ARID4B AT rich interactive domain 4B (RBP1-like)
CCDC86 coiled-coil domain containing 86
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETN2 centrin, EF-hand protein, 2
CNPY3 canopy FGF signaling regulator 3
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
FAM129A family with sequence similarity 129, member A
GAL galanin/GMAP prepropeptide
IDO1 indoleamine 2,3-dioxygenase 1
IL6ST interleukin 6 signal transducer
MEIS2 Meis homeobox 2
MRPS2 mitochondrial ribosomal protein S2
NELL2 NEL-like 2 (chicken)
NR2F2 nuclear receptor subfamily 2, group F, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
NXN nucleoredoxin
PITX1 paired-like homeodomain 1
PLK1 polo-like kinase 1
PLTP phospholipid transfer protein
SFRP1 secreted frizzled-related protein 1
SPON1 spondin 1, extracellular matrix protein
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TBL1X transducin (beta)-like 1X-linked
WDTC1 WD and tetratricopeptide repeats 1
ZEB1 zinc finger E-box binding homeobox 1