BRD-K37043259_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K37043259_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AGR2 anterior gradient 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA1 annexin A1
ANXA3 annexin A3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX2 armadillo repeat containing, X-linked 2
BLVRA biliverdin reductase A
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CERS6 ceramide synthase 6
CFD complement factor D (adipsin)
CLDN4 claudin 4
CRIP1 cysteine-rich protein 1 (intestinal)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EFNB2 ephrin-B2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
FCGBP Fc fragment of IgG binding protein
GSN gelsolin
H1FX H1 histone family, member X
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MOAP1 modulator of apoptosis 1
MX1 MX dynamin-like GTPase 1
PALLD palladin, cytoskeletal associated protein
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB25 RAB25, member RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
S100A14 S100 calcium binding protein A14
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSPAN8 tetraspanin 8
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
CXCL13 chemokine (C-X-C motif) ligand 13
KIF20A kinesin family member 20A
NR4A3 nuclear receptor subfamily 4, group A, member 3
PTPRD protein tyrosine phosphatase, receptor type, D
RHOBTB3 Rho-related BTB domain containing 3
SGK1 serum/glucocorticoid regulated kinase 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
ST18 suppression of tumorigenicity 18, zinc finger
TKTL1 transketolase-like 1
WT1 Wilms tumor 1
ZNF131 zinc finger protein 131
Funding