BRD-K37124285_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K37124285_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ASS1 argininosuccinate synthase 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTG2 BTG family, member 2
CFB complement factor B
CHN1 chimerin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELANE elastase, neutrophil expressed
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRY furry homolog (Drosophila)
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GSDMB gasdermin B
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
MPZL2 myelin protein zero-like 2
NVL nuclear VCP-like
OPN3 opsin 3
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPON1 spondin 1, extracellular matrix protein
SPRED2 sprouty-related, EVH1 domain containing 2
TCF4 transcription factor 4
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA5 annexin A5
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CRCT1 cysteine-rich C-terminal 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
FSTL1 follistatin-like 1
GOLM1 golgi membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HN1 hematological and neurological expressed 1
IGFBP4 insulin-like growth factor binding protein 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MALL mal, T-cell differentiation protein-like
MARCKSL1 MARCKS-like 1
MIA melanoma inhibitory activity
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SORD sorbitol dehydrogenase
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TMEM2 transmembrane protein 2
TSPAN3 tetraspanin 3
TUBB2B tubulin, beta 2B class IIb