BRD-K37312348_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

166 genes differentially expressed following the BRD-K37312348_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ALDOB aldolase B, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ASPN asporin
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
CALR calreticulin
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CHMP4A charged multivesicular body protein 4A
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL11A1 collagen, type XI, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRELD2 cysteine-rich with EGF-like domains 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DENND1B DENN/MADD domain containing 1B
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPT dermatopontin
DPYSL3 dihydropyrimidinase-like 3
EXT1 exostosin glycosyltransferase 1
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FZD5 frizzled class receptor 5
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
GSTA1 glutathione S-transferase alpha 1
HIC2 hypermethylated in cancer 2
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HYOU1 hypoxia up-regulated 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFRD2 interferon-related developmental regulator 2
IPO13 importin 13
IRF6 interferon regulatory factor 6
MFAP5 microfibrillar associated protein 5
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MSMB microseminoprotein, beta-
MXRA5 matrix-remodelling associated 5
NOX4 NADPH oxidase 4
ORC1 origin recognition complex, subunit 1
PBX3 pre-B-cell leukemia homeobox 3
PEG10 paternally expressed 10
PPOX protoporphyrinogen oxidase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SH3BGRL SH3 domain binding glutamate-rich protein like
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRPA signal-regulatory protein alpha
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOCS2 suppressor of cytokine signaling 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPON1 spondin 1, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SULF1 sulfatase 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF395 zinc finger protein 395
ZNF544 zinc finger protein 544
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM10 ADAM metallopeptidase domain 10
ADGRG2 adhesion G protein-coupled receptor G2
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
AKAP7 A kinase (PRKA) anchor protein 7
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BACE2 beta-site APP-cleaving enzyme 2
CA12 carbonic anhydrase XII
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CHPT1 choline phosphotransferase 1
CLU clusterin
COCH cochlin
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
ERBB2 erb-b2 receptor tyrosine kinase 2
ETV1 ets variant 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HN1 hematological and neurological expressed 1
HOXC10 homeobox C10
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
IGFBP6 insulin-like growth factor binding protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
KLC1 kinesin light chain 1
KLF2 Kruppel-like factor 2
LACTB2 lactamase, beta 2
LAPTM4B lysosomal protein transmembrane 4 beta
MAPK13 mitogen-activated protein kinase 13
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED13L mediator complex subunit 13-like
MSX1 msh homeobox 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NR1D2 nuclear receptor subfamily 1, group D, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAPOLA poly(A) polymerase alpha
PDZD8 PDZ domain containing 8
PKN2 protein kinase N2
PLCB4 phospholipase C, beta 4
RBM25 RNA binding motif protein 25
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A11 S100 calcium binding protein A11
S100A2 S100 calcium binding protein A2
SLC16A4 solute carrier family 16, member 4
SRPX sushi-repeat containing protein, X-linked
SRSF11 serine/arginine-rich splicing factor 11
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGCG UDP-glucose ceramide glucosyltransferase
URI1 URI1, prefoldin-like chaperone
WBSCR22 Williams Beuren syndrome chromosome region 22
ZBTB20 zinc finger and BTB domain containing 20
ZBTB38 zinc finger and BTB domain containing 38
Funding