| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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251 genes differentially expressed following the BRD-K37687095_AZD-8330_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABHD4 | abhydrolase domain containing 4 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADH6 | alcohol dehydrogenase 6 (class V) |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALAD | aminolevulinate dehydratase |
| ANXA4 | annexin A4 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| C5 | complement component 5 |
| CAT | catalase |
| CCNG2 | cyclin G2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CES1 | carboxylesterase 1 |
| CHL1 | cell adhesion molecule L1-like |
| CLDN8 | claudin 8 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRYAB | crystallin, alpha B |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DCAF6 | DDB1 and CUL4 associated factor 6 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial |
| DEFB1 | defensin, beta 1 |
| EBP | emopamil binding protein (sterol isomerase) |
| EFNA1 | ephrin-A1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FADS1 | fatty acid desaturase 1 |
| FADS2 | fatty acid desaturase 2 |
| FAM63A | family with sequence similarity 63, member A |
| FGA | fibrinogen alpha chain |
| FGB | fibrinogen beta chain |
| FGG | fibrinogen gamma chain |
| FOXO4 | forkhead box O4 |
| GAS1 | growth arrest-specific 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLUL | glutamate-ammonia ligase |
| GM2A | GM2 ganglioside activator |
| GOLGA8H | golgin A8 family, member H |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPM6B | glycoprotein M6B |
| GPX3 | glutathione peroxidase 3 |
| GSE1 | Gse1 coiled-coil protein |
| GSTA1 | glutathione S-transferase alpha 1 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HDAC6 | histone deacetylase 6 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HMOX1 | heme oxygenase 1 |
| HOXA5 | homeobox A5 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HSPA1A | heat shock 70kDa protein 1A |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KLHDC2 | kelch domain containing 2 |
| KYNU | kynureninase |
| LBH | limb bud and heart development |
| LMBRD1 | LMBR1 domain containing 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LSP1 | lymphocyte-specific protein 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| MVP | major vault protein |
| MXI1 | MAX interactor 1, dimerization protein |
| MYO10 | myosin X |
| NBR1 | neighbor of BRCA1 gene 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NMRK1 | nicotinamide riboside kinase 1 |
| NRCAM | neuronal cell adhesion molecule |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OPN3 | opsin 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAH | phenylalanine hydroxylase |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDGFD | platelet derived growth factor D |
| PDLIM1 | PDZ and LIM domain 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PHYH | phytanoyl-CoA 2-hydroxylase |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCARD | PYD and CARD domain containing |
| QKI | QKI, KH domain containing, RNA binding |
| QPRT | quinolinate phosphoribosyltransferase |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RXRA | retinoid X receptor, alpha |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SELENBP1 | selenium binding protein 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNN | stannin |
| SOX11 | SRY (sex determining region Y)-box 11 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| TF | transferrin |
| TMEM97 | transmembrane protein 97 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TXNIP | thioredoxin interacting protein |
| TYRP1 | tyrosinase-related protein 1 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VAT1 | vesicle amine transport 1 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| ADM | adrenomedullin |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANXA3 | annexin A3 |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ASPH | aspartate beta-hydroxylase |
| BMP4 | bone morphogenetic protein 4 |
| CALU | calumenin |
| CCDC86 | coiled-coil domain containing 86 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD58 | CD58 molecule |
| CD9 | CD9 molecule |
| CDC25A | cell division cycle 25A |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| COL1A1 | collagen, type I, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ENO1 | enolase 1, (alpha) |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EPHA2 | EPH receptor A2 |
| EREG | epiregulin |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| EXOSC4 | exosome component 4 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM3C | family with sequence similarity 3, member C |
| FAT1 | FAT atypical cadherin 1 |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| FRY | furry homolog (Drosophila) |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX | glutaredoxin (thioltransferase) |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GSPT1 | G1 to S phase transition 1 |
| GYG1 | glycogenin 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HES1 | hes family bHLH transcription factor 1 |
| HMGA1 | high mobility group AT-hook 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITGA6 | integrin, alpha 6 |
| ITGB5 | integrin, beta 5 |
| JAG1 | jagged 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KRT18 | keratin 18, type I |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LIF | leukemia inhibitory factor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MMP12 | matrix metallopeptidase 12 |
| MT1E | metallothionein 1E |
| MT1G | metallothionein 1G |
| MT1X | metallothionein 1X |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NOP16 | NOP16 nucleolar protein |
| NOP2 | NOP2 nucleolar protein |
| NOP56 | NOP56 ribonucleoprotein |
| NPY | neuropeptide Y |
| ODC1 | ornithine decarboxylase 1 |
| PDAP1 | PDGFA associated protein 1 |
| PFKP | phosphofructokinase, platelet |
| PGK1 | phosphoglycerate kinase 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAT | plasminogen activator, tissue |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PNP | purine nucleoside phosphorylase |
| PRNP | prion protein |
| RAB5C | RAB5C, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RGCC | regulator of cell cycle |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RRM2 | ribonucleotide reductase M2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A6 | S100 calcium binding protein A6 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRM | spermidine synthase |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TFF1 | trefoil factor 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM2 | transmembrane protein 2 |
| TNC | tenascin C |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TSPAN4 | tetraspanin 4 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| VCAN | versican |
| WARS | tryptophanyl-tRNA synthetase |
| WDR3 | WD repeat domain 3 |
| YBX3 | Y box binding protein 3 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
