| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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318 genes differentially expressed following the BRD-K37687095_AZD-8330_MCF10A_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADIRF | adipogenesis regulatory factor |
| ADM | adrenomedullin |
| AIM1 | absent in melanoma 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AOX1 | aldehyde oxidase 1 |
| APOD | apolipoprotein D |
| ASPN | asporin |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BBX | bobby sox homolog (Drosophila) |
| BLNK | B-cell linker |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QB | complement component 1, q subcomponent, B chain |
| C1R | complement component 1, r subcomponent |
| C1S | complement component 1, s subcomponent |
| CA12 | carbonic anhydrase XII |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CFB | complement factor B |
| CFD | complement factor D (adipsin) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLU | clusterin |
| CNN1 | calponin 1, basic, smooth muscle |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CRYAB | crystallin, alpha B |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CSTA | cystatin A (stefin A) |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DCN | decorin |
| DSP | desmoplakin |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNA1 | ephrin-A1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPS8L2 | EPS8-like 2 |
| EXPH5 | exophilin 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM134B | family with sequence similarity 134, member B |
| FBLN1 | fibulin 1 |
| FCGBP | Fc fragment of IgG binding protein |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL1 | four and a half LIM domains 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GAA | glucosidase, alpha; acid |
| GATA3 | GATA binding protein 3 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLUL | glutamate-ammonia ligase |
| GM2A | GM2 ganglioside activator |
| GOLGA8A | golgin A8 family, member A |
| GPM6B | glycoprotein M6B |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX2 | glutathione peroxidase 2 |
| GSN | gelsolin |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBB | hemoglobin, beta |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HOOK2 | hook microtubule-tethering protein 2 |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KLHL24 | kelch-like family member 24 |
| KRT15 | keratin 15, type I |
| KRT19 | keratin 19, type I |
| KRT4 | keratin 4, type II |
| LCN2 | lipocalin 2 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC16A | leucine rich repeat containing 16A |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAOA | monoamine oxidase A |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase |
| METRN | meteorin, glial cell differentiation regulator |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| MME | membrane metallo-endopeptidase |
| MUC1 | mucin 1, cell surface associated |
| MXI1 | MAX interactor 1, dimerization protein |
| MXRA5 | matrix-remodelling associated 5 |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYL9 | myosin, light chain 9, regulatory |
| NAV2 | neuron navigator 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEBL | nebulette |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRCAM | neuronal cell adhesion molecule |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDLIM1 | PDZ and LIM domain 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PPL | periplakin |
| PTN | pleiotrophin |
| PVALB | parvalbumin |
| RAB25 | RAB25, member RAS oncogene family |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RGS1 | regulator of G-protein signaling 1 |
| RHOQ | ras homolog family member Q |
| RPL31 | ribosomal protein L31 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SCPEP1 | serine carboxypeptidase 1 |
| SELENBP1 | selenium binding protein 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATA20 | spermatogenesis associated 20 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STC1 | stanniocalcin 1 |
| SULF1 | sulfatase 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TMEM30B | transmembrane protein 30B |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNS1 | tensin 1 |
| TRIM16 | tripartite motif containing 16 |
| TRIM22 | tripartite motif containing 22 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UST | uronyl-2-sulfotransferase |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WDR45 | WD repeat domain 45 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZNF264 | zinc finger protein 264 |
| ZNF652 | zinc finger protein 652 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ANPEP | alanyl (membrane) aminopeptidase |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKA | aurora kinase A |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BZW1 | basic leucine zipper and W2 domains 1 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDCA3 | cell division cycle associated 3 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CHEK2 | checkpoint kinase 2 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| COTL1 | coactosin-like F-actin binding protein 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DBF4 | DBF4 zinc finger |
| DCK | deoxycytidine kinase |
| DEPDC1 | DEP domain containing 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DONSON | downstream neighbor of SON |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| ECT2 | epithelial cell transforming 2 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EREG | epiregulin |
| EXOSC9 | exosome component 9 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FANCG | Fanconi anemia, complementation group G |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| GAL | galanin/GMAP prepropeptide |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| HAT1 | histone acetyltransferase 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H4C | histone cluster 1, H4c |
| HJURP | Holliday junction recognition protein |
| HMGA1 | high mobility group AT-hook 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HMGB2 | high mobility group box 2 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IER3 | immediate early response 3 |
| ILF2 | interleukin enhancer binding factor 2 |
| ITGB5 | integrin, beta 5 |
| KIAA0101 | KIAA0101 |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| LBR | lamin B receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NAV3 | neuron navigator 3 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NCAPG | non-SMC condensin I complex, subunit G |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY | neuropeptide Y |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PHGDH | phosphoglycerate dehydrogenase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAUR | plasminogen activator, urokinase receptor |
| PLK1 | polo-like kinase 1 |
| PNP | purine nucleoside phosphorylase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPH | phosphoserine phosphatase |
| PTX3 | pentraxin 3, long |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAD51AP1 | RAD51 associated protein 1 |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRM | spermidine synthase |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STMN1 | stathmin 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| THBS1 | thrombospondin 1 |
| TIPIN | TIMELESS interacting protein |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM97 | transmembrane protein 97 |
| TMPO | thymopoietin |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TTK | TTK protein kinase |
| TUBB4B | tubulin, beta 4B class IVb |
| TYMS | thymidylate synthetase |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP1 | ubiquitin specific peptidase 1 |
| VRK1 | vaccinia related kinase 1 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
