| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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302 genes differentially expressed following the BRD-K37687095_AZD-8330_MCF10A_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADIRF | adipogenesis regulatory factor |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATF3 | activating transcription factor 3 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTG2 | BTG family, member 2 |
| C1S | complement component 1, s subcomponent |
| C3 | complement component 3 |
| CA12 | carbonic anhydrase XII |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC53 | coiled-coil domain containing 53 |
| CD14 | CD14 molecule |
| CD24 | CD24 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFB | complement factor B |
| CFD | complement factor D (adipsin) |
| CLDN7 | claudin 7 |
| CLU | clusterin |
| COBL | cordon-bleu WH2 repeat protein |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CP | ceruloplasmin (ferroxidase) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYAB | crystallin, alpha B |
| CSTA | cystatin A (stefin A) |
| CTSD | cathepsin D |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DCN | decorin |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| DSP | desmoplakin |
| EFNA1 | ephrin-A1 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ESR1 | estrogen receptor 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM134B | family with sequence similarity 134, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBLN1 | fibulin 1 |
| FGB | fibrinogen beta chain |
| FGF9 | fibroblast growth factor 9 |
| FGG | fibrinogen gamma chain |
| FILIP1L | filamin A interacting protein 1-like |
| GAA | glucosidase, alpha; acid |
| GATA3 | GATA binding protein 3 |
| GLUL | glutamate-ammonia ligase |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSN | gelsolin |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H4H | histone cluster 1, H4h |
| HSPB8 | heat shock 22kDa protein 8 |
| IDS | iduronate 2-sulfatase |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JUND | jun D proto-oncogene |
| KLHL24 | kelch-like family member 24 |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| KRT19 | keratin 19, type I |
| KRT4 | keratin 4, type II |
| KRT8 | keratin 8, type II |
| LCN2 | lipocalin 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MATN2 | matrilin 2 |
| MEIS1 | Meis homeobox 1 |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| MUC1 | mucin 1, cell surface associated |
| MXRA5 | matrix-remodelling associated 5 |
| MYL9 | myosin, light chain 9, regulatory |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NEBL | nebulette |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLFML2A | olfactomedin-like 2A |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDLIM1 | PDZ and LIM domain 1 |
| PERP | PERP, TP53 apoptosis effector |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPL | periplakin |
| PRSS8 | protease, serine, 8 |
| RAB9A | RAB9A, member RAS oncogene family |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RGS1 | regulator of G-protein signaling 1 |
| RPL31 | ribosomal protein L31 |
| RPL39L | ribosomal protein L39-like |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| SELENBP1 | selenium binding protein 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STC1 | stanniocalcin 1 |
| STK38L | serine/threonine kinase 38 like |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TP53TG1 | TP53 target 1 (non-protein coding) |
| TRIM16 | tripartite motif containing 16 |
| TRIM22 | tripartite motif containing 22 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRCA1 | breast cancer 1, early onset |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDCA3 | cell division cycle associated 3 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| COTL1 | coactosin-like F-actin binding protein 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DBF4 | DBF4 zinc finger |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DONSON | downstream neighbor of SON |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR2 | early growth response 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EREG | epiregulin |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| ETV5 | ets variant 5 |
| EXO1 | exonuclease 1 |
| EXOSC9 | exosome component 9 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FANCG | Fanconi anemia, complementation group G |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H4C | histone cluster 1, H4c |
| HJURP | Holliday junction recognition protein |
| HMGA2 | high mobility group AT-hook 2 |
| HMGB1 | high mobility group box 1 |
| HMGB2 | high mobility group box 2 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HSPA8 | heat shock 70kDa protein 8 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| ITGB5 | integrin, beta 5 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIAA0101 | KIAA0101 |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| LBR | lamin B receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MALL | mal, T-cell differentiation protein-like |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MKI67 | marker of proliferation Ki-67 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYBPC1 | myosin binding protein C, slow type |
| NAV3 | neuron navigator 3 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHGDH | phosphoglycerate dehydrogenase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRSS3 | protease, serine, 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPH | phosphoserine phosphatase |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAD51 | RAD51 recombinase |
| RAD51AP1 | RAD51 associated protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SEPT11 | septin 11 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLBP | stem-loop binding protein |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SPHK1 | sphingosine kinase 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRM | spermidine synthase |
| STMN1 | stathmin 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TMEM97 | transmembrane protein 97 |
| TMPO | thymopoietin |
| TNC | tenascin C |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN8 | tetraspanin 8 |
| TUBB | tubulin, beta class I |
| TUBB4B | tubulin, beta 4B class IVb |
| TUBB6 | tubulin, beta 6 class V |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UPP1 | uridine phosphorylase 1 |
| USP1 | ubiquitin specific peptidase 1 |
| VRK1 | vaccinia related kinase 1 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
