BRD-K37720887_SB-525334_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-K37720887_SB-525334_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADIRF adipogenesis regulatory factor
AQP3 aquaporin 3 (Gill blood group)
ATMIN ATM interactor
BCL6 B-cell CLL/lymphoma 6
C6ORF62 chromosome 6 open reading frame 62
CALML5 calmodulin-like 5
CBR3 carbonyl reductase 3
CD36 CD36 molecule (thrombospondin receptor)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CES1 carboxylesterase 1
CNN1 calponin 1, basic, smooth muscle
COL6A3 collagen, type VI, alpha 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYAB crystallin, alpha B
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
DEFB1 defensin, beta 1
DST dystonin
EDNRB endothelin receptor type B
EPCAM epithelial cell adhesion molecule
FLNA filamin A, alpha
FMO2 flavin containing monooxygenase 2 (non-functional)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2AC histone cluster 1, H2ac
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IRS2 insulin receptor substrate 2
IVNS1ABP influenza virus NS1A binding protein
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
LMNA lamin A/C
LUM lumican
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MUC1 mucin 1, cell surface associated
MYLK myosin light chain kinase
NEBL nebulette
NPY1R neuropeptide Y receptor Y1
NREP neuronal regeneration related protein
PDGFC platelet derived growth factor C
PICALM phosphatidylinositol binding clathrin assembly protein
POSTN periostin, osteoblast specific factor
RGS4 regulator of G-protein signaling 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC4 syndecan 4
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGN serglycin
SSFA2 sperm specific antigen 2
SYNM synemin, intermediate filament protein
THBS1 thrombospondin 1
TNC tenascin C
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM29 tripartite motif containing 29
TXNIP thioredoxin interacting protein
VCAN versican
VDAC1 voltage-dependent anion channel 1
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ASRGL1 asparaginase like 1
BTG2 BTG family, member 2
CA12 carbonic anhydrase XII
CAPRIN2 caprin family member 2
CCL20 chemokine (C-C motif) ligand 20
CCND2 cyclin D2
CD200 CD200 molecule
CD34 CD34 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COPS7A COP9 signalosome subunit 7A
DLK1 delta-like 1 homolog (Drosophila)
DSE dermatan sulfate epimerase
GAL galanin/GMAP prepropeptide
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA12A heat shock 70kDa protein 12A
HTRA1 HtrA serine peptidase 1
JUNB jun B proto-oncogene
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MSX1 msh homeobox 1
MTSS1 metastasis suppressor 1
NCAM1 neural cell adhesion molecule 1
NME5 NME/NM23 family member 5
NSG1 neuron specific gene family member 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLAC8 placenta-specific 8
PLAGL1 pleiomorphic adenoma gene-like 1
PROM1 prominin 1
RHOB ras homolog family member B
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SRSF7 serine/arginine-rich splicing factor 7
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TOMM34 translocase of outer mitochondrial membrane 34
TRAF5 TNF receptor-associated factor 5
Funding