| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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189 genes differentially expressed following the BRD-K37764012_PF-3758309_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOA | aldolase A, fructose-bisphosphate |
| ANKRD10 | ankyrin repeat domain 10 |
| AREG | amphiregulin |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG2 | BTG family, member 2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD59 | CD59 molecule, complement regulatory protein |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHGB | chromogranin B |
| COL11A1 | collagen, type XI, alpha 1 |
| COL15A1 | collagen, type XV, alpha 1 |
| CTGF | connective tissue growth factor |
| CTSL | cathepsin L |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DPP4 | dipeptidyl-peptidase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| FGG | fibrinogen gamma chain |
| GATA3 | GATA binding protein 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GOLGA8A | golgin A8 family, member A |
| GOLM1 | golgi membrane protein 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HSPA1A | heat shock 70kDa protein 1A |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IDS | iduronate 2-sulfatase |
| IFI44 | interferon-induced protein 44 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INHBB | inhibin, beta B |
| IRF7 | interferon regulatory factor 7 |
| MIR22HG | MIR22 host gene |
| MMP7 | matrix metallopeptidase 7 |
| MT1E | metallothionein 1E |
| MX2 | MX dynamin-like GTPase 2 |
| NEBL | nebulette |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| OPTN | optineurin |
| OSBPL10 | oxysterol binding protein-like 10 |
| OSR2 | odd-skipped related transciption factor 2 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEG10 | paternally expressed 10 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| POSTN | periostin, osteoblast specific factor |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| QPCT | glutaminyl-peptide cyclotransferase |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RGCC | regulator of cell cycle |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC4 | syndecan 4 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNAI2 | snail family zinc finger 2 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STC1 | stanniocalcin 1 |
| STOM | stomatin |
| SVIL | supervillin |
| TBX3 | T-box 3 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM2 | transmembrane protein 2 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOP1 | topoisomerase (DNA) I |
| TPD52 | tumor protein D52 |
| TPP1 | tripeptidyl peptidase I |
| TSC22D1 | TSC22 domain family, member 1 |
| TSTA3 | tissue specific transplantation antigen P35B |
| UFM1 | ubiquitin-fold modifier 1 |
| VCL | vinculin |
| WDR45 | WD repeat domain 45 |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AUTS2 | autism susceptibility candidate 2 |
| BCHE | butyrylcholinesterase |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C7 | complement component 7 |
| CALR | calreticulin |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEP55 | centrosomal protein 55kDa |
| CIT | citron rho-interacting serine/threonine kinase |
| CLC | Charcot-Leyden crystal galectin |
| COTL1 | coactosin-like F-actin binding protein 1 |
| CSTA | cystatin A (stefin A) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DCK | deoxycytidine kinase |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DOK5 | docking protein 5 |
| ELANE | elastase, neutrophil expressed |
| ESRP1 | epithelial splicing regulatory protein 1 |
| FABP7 | fatty acid binding protein 7, brain |
| FGFR3 | fibroblast growth factor receptor 3 |
| FHL1 | four and a half LIM domains 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPX3 | glutathione peroxidase 3 |
| H2AFX | H2A histone family, member X |
| HAL | histidine ammonia-lyase |
| HIST1H4C | histone cluster 1, H4c |
| HMGB2 | high mobility group box 2 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IL1RN | interleukin 1 receptor antagonist |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| KIF20A | kinesin family member 20A |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LBR | lamin B receptor |
| LDHB | lactate dehydrogenase B |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LMO4 | LIM domain only 4 |
| LOC100505650 | uncharacterized LOC100505650 |
| MATN2 | matrilin 2 |
| MCM5 | minichromosome maintenance complex component 5 |
| MELK | maternal embryonic leucine zipper kinase |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MLANA | melan-A |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NREP | neuronal regeneration related protein |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCNA | proliferating cell nuclear antigen |
| PDLIM1 | PDZ and LIM domain 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A6 | S100 calcium binding protein A6 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMC4 | structural maintenance of chromosomes 4 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STMN1 | stathmin 1 |
| THYN1 | thymocyte nuclear protein 1 |
| TMEM47 | transmembrane protein 47 |
| TMPO | thymopoietin |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPYL5 | TSPY-like 5 |
| TUBB | tubulin, beta class I |
| TYMS | thymidylate synthetase |
| USP1 | ubiquitin specific peptidase 1 |
| WEE1 | WEE1 G2 checkpoint kinase |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZIC1 | Zic family member 1 |
| ZWINT | ZW10 interacting kinetochore protein |
