BRD-K37848908_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K37848908_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CENPU centromere protein U
DLC1 DLC1 Rho GTPase activating protein
EMP2 epithelial membrane protein 2
GPM6B glycoprotein M6B
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBB hemoglobin, beta
MAP7 microtubule-associated protein 7
NAMPT nicotinamide phosphoribosyltransferase
P3H2 prolyl 3-hydroxylase 2
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1

decreased expression

Symbol Name
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
CALR calreticulin
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
LOC100505650 uncharacterized LOC100505650
PKM pyruvate kinase, muscle
RGCC regulator of cell cycle
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZYX zyxin