Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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94 genes differentially expressed following the BRD-K37865504_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACTN1 | actinin, alpha 1 |
ALCAM | activated leukocyte cell adhesion molecule |
ANXA3 | annexin A3 |
AREG | amphiregulin |
ATF3 | activating transcription factor 3 |
BAG3 | BCL2-associated athanogene 3 |
CALD1 | caldesmon 1 |
CD24 | CD24 molecule |
CD52 | CD52 molecule |
CD59 | CD59 molecule, complement regulatory protein |
CD9 | CD9 molecule |
CHIC2 | cysteine-rich hydrophobic domain 2 |
CHMP4A | charged multivesicular body protein 4A |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CSRP1 | cysteine and glycine-rich protein 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DSP | desmoplakin |
DUSP1 | dual specificity phosphatase 1 |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GARS | glycyl-tRNA synthetase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GRB10 | growth factor receptor-bound protein 10 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
INHBA | inhibin, beta A |
JAG1 | jagged 1 |
KLF6 | Kruppel-like factor 6 |
KRT7 | keratin 7, type II |
LPIN1 | lipin 1 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAP7 | microtubule-associated protein 7 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
MSMO1 | methylsterol monooxygenase 1 |
PALLD | palladin, cytoskeletal associated protein |
PAWR | PRKC, apoptosis, WT1, regulator |
PRDX1 | peroxiredoxin 1 |
RHOB | ras homolog family member B |
S100A2 | S100 calcium binding protein A2 |
S100P | S100 calcium binding protein P |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SIK1 | salt-inducible kinase 1 |
SMS | spermine synthase |
SOX4 | SRY (sex determining region Y)-box 4 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SQSTM1 | sequestosome 1 |
THBS1 | thrombospondin 1 |
TM4SF1 | transmembrane 4 L six family member 1 |
TPM4 | tropomyosin 4 |
TUBA1A | tubulin, alpha 1a |
TXNRD1 | thioredoxin reductase 1 |
WBP5 | WW domain binding protein 5 |
Symbol | Name |
---|---|
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
APOE | apolipoprotein E |
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
CA2 | carbonic anhydrase II |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
COG2 | component of oligomeric golgi complex 2 |
COL15A1 | collagen, type XV, alpha 1 |
COL3A1 | collagen, type III, alpha 1 |
COPA | coatomer protein complex, subunit alpha |
CTSH | cathepsin H |
ELANE | elastase, neutrophil expressed |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
HBB | hemoglobin, beta |
HOXA5 | homeobox A5 |
IFITM1 | interferon induced transmembrane protein 1 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
LPAR6 | lysophosphatidic acid receptor 6 |
MDFIC | MyoD family inhibitor domain containing |
MT1E | metallothionein 1E |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
POSTN | periostin, osteoblast specific factor |
PRAME | preferentially expressed antigen in melanoma |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RNASET2 | ribonuclease T2 |
RNH1 | ribonuclease/angiogenin inhibitor 1 |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
SELENBP1 | selenium binding protein 1 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
SPON1 | spondin 1, extracellular matrix protein |
ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
TBC1D31 | TBC1 domain family, member 31 |
TFRC | transferrin receptor |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRIL | TLR4 interactor with leucine-rich repeats |
WNT5A | wingless-type MMTV integration site family, member 5A |