BRD-K37991163_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K37991163_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
C14ORF132 chromosome 14 open reading frame 132
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CRABP1 cellular retinoic acid binding protein 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
ETV1 ets variant 1
FAIM Fas apoptotic inhibitory molecule
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
GAGE3 G antigen 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
IGL immunoglobulin lambda locus
KLF9 Kruppel-like factor 9
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
NID2 nidogen 2 (osteonidogen)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIS prostaglandin I2 (prostacyclin) synthase
SCGB1D2 secretoglobin, family 1D, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SESN1 sestrin 1
SLC38A2 solute carrier family 38, member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SQSTM1 sequestosome 1
SRPX sushi-repeat containing protein, X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS2 thrombospondin 2
TXNIP thioredoxin interacting protein
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
BASP1 brain abundant, membrane attached signal protein 1
CCND1 cyclin D1
CDC25A cell division cycle 25A
COPS7A COP9 signalosome subunit 7A
CPVL carboxypeptidase, vitellogenic-like
DFNA5 deafness, autosomal dominant 5
ESR1 estrogen receptor 1
FAM46A family with sequence similarity 46, member A
FGFR3 fibroblast growth factor receptor 3
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GRWD1 glutamate-rich WD repeat containing 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
MSRB1 methionine sulfoxide reductase B1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NPY1R neuropeptide Y receptor Y1
PALLD palladin, cytoskeletal associated protein
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
SOX9 SRY (sex determining region Y)-box 9
SYT1 synaptotagmin I
TWF1 twinfilin actin binding protein 1
UBE3C ubiquitin protein ligase E3C
ZBTB18 zinc finger and BTB domain containing 18
ZYX zyxin