Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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113 genes differentially expressed following the BRD-K38340366_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACKR3 | atypical chemokine receptor 3 |
ADM | adrenomedullin |
ANGPTL2 | angiopoietin-like 2 |
ANKRD10 | ankyrin repeat domain 10 |
ASS1 | argininosuccinate synthase 1 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
CA1 | carbonic anhydrase I |
CA2 | carbonic anhydrase II |
CALML4 | calmodulin-like 4 |
CDH17 | cadherin 17, LI cadherin (liver-intestine) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DPYSL2 | dihydropyrimidinase-like 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FHL1 | four and a half LIM domains 1 |
GAL | galanin/GMAP prepropeptide |
GCH1 | GTP cyclohydrolase 1 |
GREM1 | gremlin 1, DAN family BMP antagonist |
GSDMB | gasdermin B |
H2BFS | H2B histone family, member S (pseudogene) |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BK | histone cluster 1, H2bk |
HIST1H3H | histone cluster 1, H3h |
HIST2H2BE | histone cluster 2, H2be |
IGFBP5 | insulin-like growth factor binding protein 5 |
JUN | jun proto-oncogene |
KIAA0907 | KIAA0907 |
LOX | lysyl oxidase |
LOXL2 | lysyl oxidase-like 2 |
MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase |
MT1E | metallothionein 1E |
MT1X | metallothionein 1X |
MTCL1 | microtubule crosslinking factor 1 |
MXRA7 | matrix-remodelling associated 7 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PRUNE2 | prune homolog 2 (Drosophila) |
RAP1GAP2 | RAP1 GTPase activating protein 2 |
RCAN1 | regulator of calcineurin 1 |
RPL31 | ribosomal protein L31 |
RSL1D1 | ribosomal L1 domain containing 1 |
S100A6 | S100 calcium binding protein A6 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCG2 | secretogranin II |
SCG5 | secretogranin V |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
SNAI2 | snail family zinc finger 2 |
SPON1 | spondin 1, extracellular matrix protein |
SPTSSA | serine palmitoyltransferase, small subunit A |
TCF4 | transcription factor 4 |
TFF3 | trefoil factor 3 (intestinal) |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TMOD1 | tropomodulin 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Symbol | Name |
---|---|
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
BASP1 | brain abundant, membrane attached signal protein 1 |
CD58 | CD58 molecule |
CEP170 | centrosomal protein 170kDa |
CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
COL3A1 | collagen, type III, alpha 1 |
CYB561 | cytochrome b561 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DAPK1 | death-associated protein kinase 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
EFHD1 | EF-hand domain family, member D1 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
FAM63A | family with sequence similarity 63, member A |
GDF15 | growth differentiation factor 15 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HN1 | hematological and neurological expressed 1 |
HSPB8 | heat shock 22kDa protein 8 |
IFITM3 | interferon induced transmembrane protein 3 |
INTS3 | integrator complex subunit 3 |
KIAA1033 | KIAA1033 |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
KRT7 | keratin 7, type II |
KYNU | kynureninase |
LAPTM4B | lysosomal protein transmembrane 4 beta |
MGP | matrix Gla protein |
NFIB | nuclear factor I/B |
NREP | neuronal regeneration related protein |
NRIP1 | nuclear receptor interacting protein 1 |
PCM1 | pericentriolar material 1 |
PMM2 | phosphomannomutase 2 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PSIP1 | PC4 and SFRS1 interacting protein 1 |
QKI | QKI, KH domain containing, RNA binding |
S100P | S100 calcium binding protein P |
SCYL3 | SCY1-like 3 (S. cerevisiae) |
SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SNX10 | sorting nexin 10 |
SPATS2L | spermatogenesis associated, serine-rich 2-like |
STAMBP | STAM binding protein |
SUZ12 | SUZ12 polycomb repressive complex 2 subunit |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TSPAN8 | tetraspanin 8 |
UPK1B | uroplakin 1B |
VAMP8 | vesicle-associated membrane protein 8 |
WSB1 | WD repeat and SOCS box containing 1 |
ZNF586 | zinc finger protein 586 |