BRD-K39111395_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K39111395_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
C2CD2 C2 calcium-dependent domain containing 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
LY75 lymphocyte antigen 75
MAST4 microtubule associated serine/threonine kinase family member 4
NQO1 NAD(P)H dehydrogenase, quinone 1
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SLC16A6 solute carrier family 16, member 6
SORBS2 sorbin and SH3 domain containing 2
STK17A serine/threonine kinase 17a
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
VCAM1 vascular cell adhesion molecule 1
VIM vimentin
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
CD24 CD24 molecule
CLEC2B C-type lectin domain family 2, member B
IGFBP5 insulin-like growth factor binding protein 5
IRS2 insulin receptor substrate 2
MAPK13 mitogen-activated protein kinase 13
MXRA5 matrix-remodelling associated 5
NPDC1 neural proliferation, differentiation and control, 1
POSTN periostin, osteoblast specific factor
PRKCD protein kinase C, delta
PSPH phosphoserine phosphatase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
TFRC transferrin receptor
Funding