| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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132 genes differentially expressed following the BRD-K39944607_32937_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD10 | ankyrin repeat domain 10 |
| ANXA1 | annexin A1 |
| API5 | apoptosis inhibitor 5 |
| AQP3 | aquaporin 3 (Gill blood group) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CAV2 | caveolin 2 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD44 | CD44 molecule (Indian blood group) |
| CD59 | CD59 molecule, complement regulatory protein |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| CSNK1E | casein kinase 1, epsilon |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DEFB1 | defensin, beta 1 |
| DSP | desmoplakin |
| FAM129A | family with sequence similarity 129, member A |
| FGL2 | fibrinogen-like 2 |
| FHOD3 | formin homology 2 domain containing 3 |
| GAL | galanin/GMAP prepropeptide |
| GPX3 | glutathione peroxidase 3 |
| HIC2 | hypermethylated in cancer 2 |
| HSPB8 | heat shock 22kDa protein 8 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGL | immunoglobulin lambda locus |
| JAG1 | jagged 1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KLK10 | kallikrein-related peptidase 10 |
| KLK5 | kallikrein-related peptidase 5 |
| KLK7 | kallikrein-related peptidase 7 |
| KLK8 | kallikrein-related peptidase 8 |
| KRT1 | keratin 1, type II |
| KRT14 | keratin 14, type I |
| KRT17 | keratin 17, type I |
| KRT23 | keratin 23, type I |
| KRT6B | keratin 6B, type II |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LOR | loricrin |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MDK | midkine (neurite growth-promoting factor 2) |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MT1E | metallothionein 1E |
| MYOF | myoferlin |
| PCDH7 | protocadherin 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PERP | PERP, TP53 apoptosis effector |
| POSTN | periostin, osteoblast specific factor |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| S100A7 | S100 calcium binding protein A7 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPON1 | spondin 1, extracellular matrix protein |
| STC1 | stanniocalcin 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TMEM45A | transmembrane protein 45A |
| TUBB2A | tubulin, beta 2A class IIa |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WLS | wntless Wnt ligand secretion mediator |
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| AK1 | adenylate kinase 1 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| AMDHD2 | amidohydrolase domain containing 2 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CIRBP | cold inducible RNA binding protein |
| COL5A1 | collagen, type V, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| EDF1 | endothelial differentiation-related factor 1 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
| GALE | UDP-galactose-4-epimerase |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 |
| GPI | glucose-6-phosphate isomerase |
| GPX1 | glutathione peroxidase 1 |
| H1F0 | H1 histone family, member 0 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| JUN | jun proto-oncogene |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF2 | Kruppel-like factor 2 |
| KRT13 | keratin 13, type I |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LTF | lactotransferrin |
| MAGED1 | melanoma antigen family D1 |
| MALL | mal, T-cell differentiation protein-like |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METRN | meteorin, glial cell differentiation regulator |
| MGP | matrix Gla protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NOTCH1 | notch 1 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| ODC1 | ornithine decarboxylase 1 |
| PENK | proenkephalin |
| PGC | progastricsin (pepsinogen C) |
| PGD | phosphogluconate dehydrogenase |
| PLAU | plasminogen activator, urokinase |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PRAF2 | PRA1 domain family, member 2 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RPS11 | ribosomal protein S11 |
| SCAND1 | SCAN domain containing 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGM2 | transglutaminase 2 |
| TPM2 | tropomyosin 2 (beta) |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| ZBTB18 | zinc finger and BTB domain containing 18 |
