| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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146 genes differentially expressed following the BRD-K40175214_torin-1_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABHD4 | abhydrolase domain containing 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CCDC28A | coiled-coil domain containing 28A |
| CD14 | CD14 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COL4A5 | collagen, type IV, alpha 5 |
| CTGF | connective tissue growth factor |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DST | dystonin |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNA1 | ephrin-A1 |
| EIF4B | eukaryotic translation initiation factor 4B |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FOXO4 | forkhead box O4 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GLUL | glutamate-ammonia ligase |
| GMPR | guanosine monophosphate reductase |
| HBP1 | HMG-box transcription factor 1 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H1C | histone cluster 1, H1c |
| HMOX1 | heme oxygenase 1 |
| HNMT | histamine N-methyltransferase |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KLHDC2 | kelch domain containing 2 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LXN | latexin |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MTSS1 | metastasis suppressor 1 |
| MVP | major vault protein |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| RAB13 | RAB13, member RAS oncogene family |
| RAB31 | RAB31, member RAS oncogene family |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RNMT | RNA (guanine-7-) methyltransferase |
| RTN2 | reticulon 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TPP1 | tripeptidyl peptidase I |
| TRAPPC6A | trafficking protein particle complex 6A |
| TXNIP | thioredoxin interacting protein |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACP5 | acid phosphatase 5, tartrate resistant |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| AK4 | adenylate kinase 4 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP5G3 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) |
| BMP2 | bone morphogenetic protein 2 |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CCDC86 | coiled-coil domain containing 86 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CD24 | CD24 molecule |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CTSE | cathepsin E |
| CYCS | cytochrome c, somatic |
| DHCR24 | 24-dehydrocholesterol reductase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ENO1 | enolase 1, (alpha) |
| FEN1 | flap structure-specific endonuclease 1 |
| FERMT1 | fermitin family member 1 |
| FHL1 | four and a half LIM domains 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GGCT | gamma-glutamylcyclotransferase |
| GPI | glucose-6-phosphate isomerase |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GTPBP8 | GTP-binding protein 8 (putative) |
| HAT1 | histone acetyltransferase 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HN1 | hematological and neurological expressed 1 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL1RN | interleukin 1 receptor antagonist |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| MAP1B | microtubule-associated protein 1B |
| MCM10 | minichromosome maintenance complex component 10 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MINA | MYC induced nuclear antigen |
| MRPL3 | mitochondrial ribosomal protein L3 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MTCH2 | mitochondrial carrier 2 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NOP56 | NOP56 ribonucleoprotein |
| NPTX2 | neuronal pentraxin II |
| NRG1 | neuregulin 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFM4 | olfactomedin 4 |
| PCNA | proliferating cell nuclear antigen |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PFKP | phosphofructokinase, platelet |
| PGK1 | phosphoglycerate kinase 1 |
| PNP | purine nucleoside phosphorylase |
| PPIF | peptidylprolyl isomerase F |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRDX2 | peroxiredoxin 2 |
| PRNP | prion protein |
| PRSS3 | protease, serine, 3 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| SFN | stratifin |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR1A | small proline-rich protein 1A |
| SRM | spermidine synthase |
| TFDP1 | transcription factor Dp-1 |
| TFRC | transferrin receptor |
| TGFA | transforming growth factor, alpha |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TUBB6 | tubulin, beta 6 class V |
| TYMS | thymidylate synthetase |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| UFM1 | ubiquitin-fold modifier 1 |
| VIM | vimentin |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
