| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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185 genes differentially expressed following the BRD-K40175214_torin-1_BT20_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABHD4 | abhydrolase domain containing 4 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| CASC3 | cancer susceptibility candidate 3 |
| CAST | calpastatin |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCDC28A | coiled-coil domain containing 28A |
| CD46 | CD46 molecule, complement regulatory protein |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD59 | CD59 molecule, complement regulatory protein |
| CDK19 | cyclin-dependent kinase 19 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CTGF | connective tissue growth factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYTH1 | cytohesin 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DST | dystonin |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EFNA1 | ephrin-A1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FBN2 | fibrillin 2 |
| FOXO4 | forkhead box O4 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GPR137B | G protein-coupled receptor 137B |
| H1F0 | H1 histone family, member 0 |
| HBP1 | HMG-box transcription factor 1 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HECA | headcase homolog (Drosophila) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMOX1 | heme oxygenase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| INSR | insulin receptor |
| JMJD1C | jumonji domain containing 1C |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIAA0355 | KIAA0355 |
| KLHDC2 | kelch domain containing 2 |
| KLHL24 | kelch-like family member 24 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LINC00342 | long intergenic non-protein coding RNA 342 |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| LXN | latexin |
| MARCKSL1 | MARCKS-like 1 |
| MCOLN1 | mucolipin 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MLPH | melanophilin |
| MPO | myeloperoxidase |
| MXI1 | MAX interactor 1, dimerization protein |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAV2 | neuron navigator 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEBL | nebulette |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RNASET2 | ribonuclease T2 |
| RND3 | Rho family GTPase 3 |
| RTN2 | reticulon 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERINC1 | serine incorporator 1 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 |
| SLC35E2B | solute carrier family 35, member E2B |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SMAD3 | SMAD family member 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBX3 | T-box 3 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| THBS1 | thrombospondin 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM63A | transmembrane protein 63A |
| TPP1 | tripeptidyl peptidase I |
| TSPAN4 | tetraspanin 4 |
| VAT1 | vesicle amine transport 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| AK2 | adenylate kinase 2 |
| AK4 | adenylate kinase 4 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| C3 | complement component 3 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDK4 | cyclin-dependent kinase 4 |
| CENPU | centromere protein U |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CYCS | cytochrome c, somatic |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EBP | emopamil binding protein (sterol isomerase) |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| ENO1 | enolase 1, (alpha) |
| FAM57A | family with sequence similarity 57, member A |
| FASN | fatty acid synthase |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GSTA1 | glutathione S-transferase alpha 1 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HN1 | hematological and neurological expressed 1 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| KLF4 | Kruppel-like factor 4 (gut) |
| LRRC59 | leucine rich repeat containing 59 |
| MALL | mal, T-cell differentiation protein-like |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM6 | minichromosome maintenance complex component 6 |
| MELK | maternal embryonic leucine zipper kinase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MPHOSPH6 | M-phase phosphoprotein 6 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MTCH2 | mitochondrial carrier 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NOP16 | NOP16 nucleolar protein |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PFKP | phosphofructokinase, platelet |
| PGAM1 | phosphoglycerate mutase 1 (brain) |
| PGM1 | phosphoglucomutase 1 |
| PNP | purine nucleoside phosphorylase |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRPF4 | pre-mRNA processing factor 4 |
| PRSS3 | protease, serine, 3 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RRM2 | ribonucleotide reductase M2 |
| RTN1 | reticulon 1 |
| S100A6 | S100 calcium binding protein A6 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SQLE | squalene epoxidase |
| SRM | spermidine synthase |
| STRA13 | stimulated by retinoic acid 13 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TFRC | transferrin receptor |
| TGFA | transforming growth factor, alpha |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB | tubulin, beta class I |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB6 | tubulin, beta 6 class V |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZWINT | ZW10 interacting kinetochore protein |
