| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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170 genes differentially expressed following the BRD-K40175214_torin-1_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACTN1 | actinin, alpha 1 |
| AGTR1 | angiotensin II receptor, type 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD58 | CD58 molecule |
| CD9 | CD9 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CST1 | cystatin SN |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH1 | cytohesin 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DST | dystonin |
| DUSP10 | dual specificity phosphatase 10 |
| EDN1 | endothelin 1 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| EVI2A | ecotropic viral integration site 2A |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FCMR | Fc fragment of IgM receptor |
| FGG | fibrinogen gamma chain |
| FHL2 | four and a half LIM domains 2 |
| FN1 | fibronectin 1 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GLRX | glutaredoxin (thioltransferase) |
| GOLGA8A | golgin A8 family, member A |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H1F0 | H1 histone family, member 0 |
| IER3 | immediate early response 3 |
| IGHM | immunoglobulin heavy constant mu |
| IRS2 | insulin receptor substrate 2 |
| ITGB5 | integrin, beta 5 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LOC100272216 | uncharacterized LOC100272216 |
| LPIN2 | lipin 2 |
| LPXN | leupaxin |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTSS1 | metastasis suppressor 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRKCA | protein kinase C, alpha |
| PXDC1 | PX domain containing 1 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| REG1A | regenerating islet-derived 1 alpha |
| RGS10 | regulator of G-protein signaling 10 |
| RIOK3 | RIO kinase 3 |
| SERINC5 | serine incorporator 5 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SMAD3 | SMAD family member 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SQSTM1 | sequestosome 1 |
| TBC1D4 | TBC1 domain family, member 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFF1 | trefoil factor 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THBS1 | thrombospondin 1 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPM1 | tropomyosin 1 (alpha) |
| WDR45 | WD repeat domain 45 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| YBX3 | Y box binding protein 3 |
| Symbol | Name |
|---|---|
| ADI1 | acireductone dioxygenase 1 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ANK2 | ankyrin 2, neuronal |
| AQP1 | aquaporin 1 (Colton blood group) |
| ASS1 | argininosuccinate synthase 1 |
| AURKB | aurora kinase B |
| B3GNT1 | |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CA12 | carbonic anhydrase XII |
| CCNA2 | cyclin A2 |
| CDC20 | cell division cycle 20 |
| CDC42 | cell division cycle 42 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPU | centromere protein U |
| CETN2 | centrin, EF-hand protein, 2 |
| CHEK2 | checkpoint kinase 2 |
| CLU | clusterin |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| CPE | carboxypeptidase E |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DBF4 | DBF4 zinc finger |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DCN | decorin |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR7 | 7-dehydrocholesterol reductase |
| EBP | emopamil binding protein (sterol isomerase) |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FRZB | frizzled-related protein |
| GAL | galanin/GMAP prepropeptide |
| GCH1 | GTP cyclohydrolase 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPM6B | glycoprotein M6B |
| GSTP1 | glutathione S-transferase pi 1 |
| HAT1 | histone acetyltransferase 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IGL | immunoglobulin lambda locus |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KIAA0101 | KIAA0101 |
| KRT19 | keratin 19, type I |
| LTF | lactotransferrin |
| LUM | lumican |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MELK | maternal embryonic leucine zipper kinase |
| METTL7A | methyltransferase like 7A |
| MFAP4 | microfibrillar-associated protein 4 |
| MSMO1 | methylsterol monooxygenase 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NCAPG | non-SMC condensin I complex, subunit G |
| POSTN | periostin, osteoblast specific factor |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRDX4 | peroxiredoxin 4 |
| PTTG1 | pituitary tumor-transforming 1 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| QDPR | quinoid dihydropteridine reductase |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM2 | ribonucleotide reductase M2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SMAD1 | SMAD family member 1 |
| SQLE | squalene epoxidase |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOR3A | torsin family 3, member A |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIP13 | thyroid hormone receptor interactor 13 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
