Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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95 genes differentially expressed following the BRD-K40175214_torin-1_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKAP7 | A kinase (PRKA) anchor protein 7 |
ANXA2 | annexin A2 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
BCL6 | B-cell CLL/lymphoma 6 |
BTN3A2 | butyrophilin, subfamily 3, member A2 |
CALML5 | calmodulin-like 5 |
CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
CCL5 | chemokine (C-C motif) ligand 5 |
CD36 | CD36 molecule (thrombospondin receptor) |
CD8A | CD8a molecule |
CHRDL1 | chordin-like 1 |
CLU | clusterin |
CPVL | carboxypeptidase, vitellogenic-like |
CST3 | cystatin C |
DSP | desmoplakin |
F2R | coagulation factor II (thrombin) receptor |
FABP7 | fatty acid binding protein 7, brain |
FAM13A | family with sequence similarity 13, member A |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
GATA3 | GATA binding protein 3 |
GATA6 | GATA binding protein 6 |
GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
GZMK | granzyme K (granzyme 3; tryptase II) |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IGL | immunoglobulin lambda locus |
KRT14 | keratin 14, type I |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
NKG7 | natural killer cell granule protein 7 |
NMT2 | N-myristoyltransferase 2 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
NRN1 | neuritin 1 |
PRF1 | perforin 1 (pore forming protein) |
PTN | pleiotrophin |
S100A10 | S100 calcium binding protein A10 |
SATB1 | SATB homeobox 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SELL | selectin L |
SEPP1 | selenoprotein P, plasma, 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SOX9 | SRY (sex determining region Y)-box 9 |
STK17A | serine/threonine kinase 17a |
TM4SF1 | transmembrane 4 L six family member 1 |
TSC22D1 | TSC22 domain family, member 1 |
TSPAN13 | tetraspanin 13 |
TXNL4B | thioredoxin-like 4B |
Symbol | Name |
---|---|
ALOX5 | arachidonate 5-lipoxygenase |
CACYBP | calcyclin binding protein |
CBR3 | carbonyl reductase 3 |
CD24 | CD24 molecule |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHGB | chromogranin B |
CTSZ | cathepsin Z |
DCN | decorin |
DDIT4 | DNA-damage-inducible transcript 4 |
DEPTOR | DEP domain containing MTOR-interacting protein |
EIF5B | eukaryotic translation initiation factor 5B |
FGFR2 | fibroblast growth factor receptor 2 |
FRZB | frizzled-related protein |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HSPA1A | heat shock 70kDa protein 1A |
HSPA2 | heat shock 70kDa protein 2 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
MAT2A | methionine adenosyltransferase II, alpha |
MMP7 | matrix metallopeptidase 7 |
MT1E | metallothionein 1E |
MT1F | metallothionein 1F |
MT1X | metallothionein 1X |
MTF2 | metal response element binding transcription factor 2 |
MUC1 | mucin 1, cell surface associated |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
ORC1 | origin recognition complex, subunit 1 |
PCDH9 | protocadherin 9 |
PLN | phospholamban |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRUNE2 | prune homolog 2 (Drosophila) |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SEC62 | SEC62 homolog (S. cerevisiae) |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
SNAP25 | synaptosomal-associated protein, 25kDa |
SRGN | serglycin |
SST | somatostatin |
TBX2 | T-box 2 |
TDO2 | tryptophan 2,3-dioxygenase |
TM4SF4 | transmembrane 4 L six family member 4 |
TMED2 | transmembrane emp24 domain trafficking protein 2 |
TMEM47 | transmembrane protein 47 |
TMX4 | thioredoxin-related transmembrane protein 4 |
TUBA4A | tubulin, alpha 4a |
VAMP8 | vesicle-associated membrane protein 8 |