BRD-K40175214_torin-1_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K40175214_torin-1_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOE apolipoprotein E
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EGR1 early growth response 1
FBN2 fibrillin 2
FBXO11 F-box protein 11
FOXG1 forkhead box G1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
GRB10 growth factor receptor-bound protein 10
HLA-B major histocompatibility complex, class I, B
IL6ST interleukin 6 signal transducer
KRT15 keratin 15, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MED24 mediator complex subunit 24
MET MET proto-oncogene, receptor tyrosine kinase
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRIP1 nuclear receptor interacting protein 1
PDGFD platelet derived growth factor D
PNKP polynucleotide kinase 3'-phosphatase
PTN pleiotrophin
RAD21 RAD21 homolog (S. pombe)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RPL39L ribosomal protein L39-like
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
TESC tescalcin
TFPI2 tissue factor pathway inhibitor 2
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
CCND1 cyclin D1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CPE carboxypeptidase E
CSRP1 cysteine and glycine-rich protein 1
EPHA3 EPH receptor A3
GCH1 GTP cyclohydrolase 1
GREM1 gremlin 1, DAN family BMP antagonist
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MFAP5 microfibrillar associated protein 5
NNMT nicotinamide N-methyltransferase
PODXL podocalyxin-like
SPINK1 serine peptidase inhibitor, Kazal type 1
TES testin LIM domain protein
Funding