BRD-K40645748_mefloquine_A375_6.0_h_10.0_um Gene Set
Genes
30 genes differentially expressed following the BRD-K40645748_mefloquine_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
AKR1C1
|
aldo-keto reductase family 1, member C1
|
|
CHI3L2
|
chitinase 3-like 2
|
|
CLU
|
clusterin
|
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
|
|
CXCL6
|
chemokine (C-X-C motif) ligand 6
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
EPHX1
|
epoxide hydrolase 1, microsomal (xenobiotic)
|
|
FZD7
|
frizzled class receptor 7
|
|
HMOX1
|
heme oxygenase 1
|
|
HSPA6
|
heat shock 70kDa protein 6 (HSP70B')
|
|
IFI30
|
interferon, gamma-inducible protein 30
|
|
KRT15
|
keratin 15, type I
|
|
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
|
NTS
|
neurotensin
|
|
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2
|
|
TXNRD1
|
thioredoxin reductase 1
|
decreased expression
| Symbol |
Name |
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
|
AREG
|
amphiregulin
|
|
DKK3
|
dickkopf WNT signaling pathway inhibitor 3
|
|
GJA1
|
gap junction protein, alpha 1, 43kDa
|
|
LMO3
|
LIM domain only 3 (rhombotin-like 2)
|
|
NEBL
|
nebulette
|
|
SDC1
|
syndecan 1
|
|
SPARC
|
secreted protein, acidic, cysteine-rich (osteonectin)
|
|
TFRC
|
transferrin receptor
|
|
THBS2
|
thrombospondin 2
|
|
TRIM2
|
tripartite motif containing 2
|
|
XIST
|
X inactive specific transcript (non-protein coding)
|
