BRD-K40887525_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K40887525_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
BST2 bone marrow stromal cell antigen 2
CST3 cystatin C
CSTA cystatin A (stefin A)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GMDS GDP-mannose 4,6-dehydratase
GPATCH8 G patch domain containing 8
GRAMD1B GRAM domain containing 1B
KRT19 keratin 19, type I
MAMLD1 mastermind-like domain containing 1
METTL7A methyltransferase like 7A
MRPS30 mitochondrial ribosomal protein S30
PLEC plectin
RBM25 RNA binding motif protein 25
S100A11 S100 calcium binding protein A11
S100P S100 calcium binding protein P
SFN stratifin
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STXBP6 syntaxin binding protein 6 (amisyn)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL2 angiopoietin-like 2
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD1E CD1e molecule
CD200 CD200 molecule
CD58 CD58 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYD dihydropyrimidine dehydrogenase
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
FSD1 fibronectin type III and SPRY domain containing 1
GJA1 gap junction protein, alpha 1, 43kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNMT histamine N-methyltransferase
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFI16 interferon, gamma-inducible protein 16
JAG1 jagged 1
MAOA monoamine oxidase A
MME membrane metallo-endopeptidase
NID1 nidogen 1
PCLO piccolo presynaptic cytomatrix protein
PDLIM3 PDZ and LIM domain 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTPRK protein tyrosine phosphatase, receptor type, K
QKI QKI, KH domain containing, RNA binding
REEP1 receptor accessory protein 1
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
SH3BGRL SH3 domain binding glutamate-rich protein like
SNX7 sorting nexin 7
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TCF4 transcription factor 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUSC3 tumor suppressor candidate 3
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
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