BRD-K40919711_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K40919711_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
ARPP19 cAMP-regulated phosphoprotein, 19kDa
AZIN1 antizyme inhibitor 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CLEC7A C-type lectin domain family 7, member A
CLIC5 chloride intracellular channel 5
COL11A1 collagen, type XI, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DOK5 docking protein 5
EGR1 early growth response 1
FGFR3 fibroblast growth factor receptor 3
FZD6 frizzled class receptor 6
GATA6 GATA binding protein 6
GREB1 growth regulation by estrogen in breast cancer 1
GSTM3 glutathione S-transferase mu 3 (brain)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA13 heat shock protein 70kDa family, member 13
IL6 interleukin 6
KDM3A lysine (K)-specific demethylase 3A
MXI1 MAX interactor 1, dimerization protein
PEG3 paternally expressed 3
PID1 phosphotyrosine interaction domain containing 1
PLAGL1 pleiomorphic adenoma gene-like 1
QKI QKI, KH domain containing, RNA binding
SATB2 SATB homeobox 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TBPL1 TBP-like 1
TES testin LIM domain protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN7 tetraspanin 7
TXNIP thioredoxin interacting protein
VCAN versican
ZBTB18 zinc finger and BTB domain containing 18
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
AQP3 aquaporin 3 (Gill blood group)
C3 complement component 3
CCND1 cyclin D1
CCNF cyclin F
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CYB5A cytochrome b5 type A (microsomal)
DACH1 dachshund family transcription factor 1
DUSP4 dual specificity phosphatase 4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA3 GATA binding protein 3
H3F3B H3 histone, family 3B (H3.3B)
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
MEIS1 Meis homeobox 1
MMP7 matrix metallopeptidase 7
ODAM odontogenic, ameloblast asssociated
PIP prolactin-induced protein
PLTP phospholipid transfer protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SYBU syntabulin (syntaxin-interacting)
TACSTD2 tumor-associated calcium signal transducer 2
TESC tescalcin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
WFDC2 WAP four-disulfide core domain 2