BRD-K41240505_5-(furan-2-yl)-7-(4-(furan-3-ylmethyl)piperazin-1-yl)-2-(p-tolyl)pyrazolo[1,5-a]pyrimidine KUC106904N_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

15 genes differentially expressed following the BRD-K41240505_5-(furan-2-yl)-7-(4-(furan-3-ylmethyl)piperazin-1-yl)-2-(p-tolyl)pyrazolo[1,5-a]pyrimidine KUC106904N_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXT1 exostosin glycosyltransferase 1
HOPX HOP homeobox
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
PDZK1IP1 PDZK1 interacting protein 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
PENK proenkephalin
RBP1 retinol binding protein 1, cellular
RPS11 ribosomal protein S11
SRPX sushi-repeat containing protein, X-linked
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TOB1 transducer of ERBB2, 1
Funding