BRD-K41557448_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K41557448_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CCR2 chemokine (C-C motif) receptor 2
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSTA cystatin A (stefin A)
CXCL11 chemokine (C-X-C motif) ligand 11
GIMAP6 GTPase, IMAP family member 6
GNAS GNAS complex locus
HBB hemoglobin, beta
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT15 keratin 15, type I
OLFM4 olfactomedin 4
PECAM1 platelet/endothelial cell adhesion molecule 1
RTN1 reticulon 1
TFF1 trefoil factor 1
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
WDR7 WD repeat domain 7

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
CADM1 cell adhesion molecule 1
CDC45 cell division cycle 45
DEFB1 defensin, beta 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
NVL nuclear VCP-like
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)