Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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85 genes differentially expressed following the BRD-K41895714_AS-605240_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAM10 | ADAM metallopeptidase domain 10 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
APOC1 | apolipoprotein C-I |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDH3 | cadherin 3, type 1, P-cadherin (placental) |
CDK5RAP3 | CDK5 regulatory subunit associated protein 3 |
COMT | catechol-O-methyltransferase |
CRYAB | crystallin, alpha B |
CSTA | cystatin A (stefin A) |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
ENO2 | enolase 2 (gamma, neuronal) |
EVL | Enah/Vasp-like |
GLS | glutaminase |
GPER1 | G protein-coupled estrogen receptor 1 |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HOXA5 | homeobox A5 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
KRT5 | keratin 5, type II |
LBH | limb bud and heart development |
MARCKSL1 | MARCKS-like 1 |
MEIS2 | Meis homeobox 2 |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
MSRB2 | methionine sulfoxide reductase B2 |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
NREP | neuronal regeneration related protein |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PRKCD | protein kinase C, delta |
REEP1 | receptor accessory protein 1 |
ROGDI | rogdi homolog (Drosophila) |
SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
SELENBP1 | selenium binding protein 1 |
SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
SNX11 | sorting nexin 11 |
SPATA20 | spermatogenesis associated 20 |
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPM2 | tropomyosin 2 (beta) |
WFDC2 | WAP four-disulfide core domain 2 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADD3 | adducin 3 (gamma) |
ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
ASPN | asporin |
CCND1 | cyclin D1 |
CCND2 | cyclin D2 |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
COL2A1 | collagen, type II, alpha 1 |
COMP | cartilage oligomeric matrix protein |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CYBA | cytochrome b-245, alpha polypeptide |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DUSP4 | dual specificity phosphatase 4 |
EGR1 | early growth response 1 |
EIF5A | eukaryotic translation initiation factor 5A |
EPCAM | epithelial cell adhesion molecule |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FBN1 | fibrillin 1 |
GLIPR1 | GLI pathogenesis-related 1 |
GOLM1 | golgi membrane protein 1 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HELLS | helicase, lymphoid-specific |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
HSPA8 | heat shock 70kDa protein 8 |
ITGB5 | integrin, beta 5 |
MFAP5 | microfibrillar associated protein 5 |
MT1E | metallothionein 1E |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
NT5E | 5'-nucleotidase, ecto (CD73) |
PLSCR1 | phospholipid scramblase 1 |
PPARG | peroxisome proliferator-activated receptor gamma |
PRSS3 | protease, serine, 3 |
RPL39L | ribosomal protein L39-like |
S100P | S100 calcium binding protein P |
SPP1 | secreted phosphoprotein 1 |
SQRDL | sulfide quinone reductase-like (yeast) |
SRGN | serglycin |
THBS4 | thrombospondin 4 |
TIAM1 | T-cell lymphoma invasion and metastasis 1 |
TLR4 | toll-like receptor 4 |
TM4SF1 | transmembrane 4 L six family member 1 |