Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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111 genes differentially expressed following the BRD-K42098891_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
AGR2 | anterior gradient 2 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
CA12 | carbonic anhydrase XII |
CD24 | CD24 molecule |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
DEPTOR | DEP domain containing MTOR-interacting protein |
DHCR7 | 7-dehydrocholesterol reductase |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
EBP | emopamil binding protein (sterol isomerase) |
EMP3 | epithelial membrane protein 3 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
HEPH | hephaestin |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IGHD | immunoglobulin heavy constant delta |
IGHM | immunoglobulin heavy constant mu |
IGLJ3 | immunoglobulin lambda joining 3 |
INSIG1 | insulin induced gene 1 |
JCHAIN | joining chain of multimeric IgA and IgM |
KIAA0753 | KIAA0753 |
KLF4 | Kruppel-like factor 4 (gut) |
KRT19 | keratin 19, type I |
LY75 | lymphocyte antigen 75 |
MAGED1 | melanoma antigen family D1 |
MAP7 | microtubule-associated protein 7 |
MBNL1 | muscleblind-like splicing regulator 1 |
MRPS30 | mitochondrial ribosomal protein S30 |
MSMO1 | methylsterol monooxygenase 1 |
MTUS1 | microtubule associated tumor suppressor 1 |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
MYO6 | myosin VI |
PCDH9 | protocadherin 9 |
PLS1 | plastin 1 |
POU2AF1 | POU class 2 associating factor 1 |
RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
SQLE | squalene epoxidase |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TM4SF1 | transmembrane 4 L six family member 1 |
TSPAN13 | tetraspanin 13 |
TSPAN8 | tetraspanin 8 |
TST | thiosulfate sulfurtransferase (rhodanese) |
XK | X-linked Kx blood group |
Symbol | Name |
---|---|
A2M | alpha-2-macroglobulin |
ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADM | adrenomedullin |
BCHE | butyrylcholinesterase |
BTG3 | BTG family, member 3 |
CA2 | carbonic anhydrase II |
CAMP | cathelicidin antimicrobial peptide |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
COL1A2 | collagen, type I, alpha 2 |
CRISP3 | cysteine-rich secretory protein 3 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DEFA4 | defensin, alpha 4, corticostatin |
DPP4 | dipeptidyl-peptidase 4 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EPAS1 | endothelial PAS domain protein 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM129A | family with sequence similarity 129, member A |
FILIP1L | filamin A interacting protein 1-like |
FPGS | folylpolyglutamate synthase |
GJA1 | gap junction protein, alpha 1, 43kDa |
HCAR3 | hydroxycarboxylic acid receptor 3 |
IGFBP5 | insulin-like growth factor binding protein 5 |
LCN2 | lipocalin 2 |
LOX | lysyl oxidase |
LRRC17 | leucine rich repeat containing 17 |
NID1 | nidogen 1 |
NID2 | nidogen 2 (osteonidogen) |
NXN | nucleoredoxin |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PPL | periplakin |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
PXDN | peroxidasin |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
RBP1 | retinol binding protein 1, cellular |
RGCC | regulator of cell cycle |
S100A12 | S100 calcium binding protein A12 |
S100A8 | S100 calcium binding protein A8 |
S100A9 | S100 calcium binding protein A9 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SOX11 | SRY (sex determining region Y)-box 11 |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
STC1 | stanniocalcin 1 |
TCEA2 | transcription elongation factor A (SII), 2 |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TFPI2 | tissue factor pathway inhibitor 2 |
WASF1 | WAS protein family, member 1 |
WLS | wntless Wnt ligand secretion mediator |
WNT5A | wingless-type MMTV integration site family, member 5A |
XIST | X inactive specific transcript (non-protein coding) |