BRD-K42098891_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K42098891_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIRC2 baculoviral IAP repeat containing 2
CA12 carbonic anhydrase XII
CD52 CD52 molecule
CLCA4 chloride channel accessory 4
CNN3 calponin 3, acidic
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSC3 desmocollin 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR3 fibroblast growth factor receptor 3
HIST1H1C histone cluster 1, H1c
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MDK midkine (neurite growth-promoting factor 2)
MMP7 matrix metallopeptidase 7
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
CYBA cytochrome b-245, alpha polypeptide
DPYSL3 dihydropyrimidinase-like 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GABPB1 GA binding protein transcription factor, beta subunit 1
KRT18 keratin 18, type I
MAP7 microtubule-associated protein 7
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
THAP11 THAP domain containing 11
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13