| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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85 genes differentially expressed following the BRD-K42191735_buparlisib_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ANKRD10 | ankyrin repeat domain 10 |
| BRD8 | bromodomain containing 8 |
| CCNG2 | cyclin G2 |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| COLEC12 | collectin sub-family member 12 |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DST | dystonin |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FZD6 | frizzled class receptor 6 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 |
| GPR137B | G protein-coupled receptor 137B |
| GRN | granulin |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BK | histone cluster 1, H2bk |
| HMOX1 | heme oxygenase 1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IRS2 | insulin receptor substrate 2 |
| ISCU | iron-sulfur cluster assembly enzyme |
| KLHDC2 | kelch domain containing 2 |
| LAMB1 | laminin, beta 1 |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| METTL7A | methyltransferase like 7A |
| NBR1 | neighbor of BRCA1 gene 1 |
| PDGFD | platelet derived growth factor D |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PERP | PERP, TP53 apoptosis effector |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| RAB31 | RAB31, member RAS oncogene family |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| RTN2 | reticulon 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS3 | tensin 3 |
| TXNIP | thioredoxin interacting protein |
| VWA5A | von Willebrand factor A domain containing 5A |
| Symbol | Name |
|---|---|
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC42 | cell division cycle 42 |
| CDC6 | cell division cycle 6 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENO1 | enolase 1, (alpha) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM57A | family with sequence similarity 57, member A |
| G0S2 | G0/G1 switch 2 |
| GPI | glucose-6-phosphate isomerase |
| HK2 | hexokinase 2 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IFRD2 | interferon-related developmental regulator 2 |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| LPL | lipoprotein lipase |
| MALL | mal, T-cell differentiation protein-like |
| MCM3 | minichromosome maintenance complex component 3 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| PNP | purine nucleoside phosphorylase |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| RPL27A | ribosomal protein L27a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| SET | SET nuclear proto-oncogene |
| SFN | stratifin |
| SNRPE | small nuclear ribonucleoprotein polypeptide E |
| STIP1 | stress-induced phosphoprotein 1 |
| VCAN | versican |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
