| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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63 genes differentially expressed following the BRD-K42191735_buparlisib_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CAPN6 | calpain 6 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| COL9A3 | collagen, type IX, alpha 3 |
| COLEC12 | collectin sub-family member 12 |
| ELMO1 | engulfment and cell motility 1 |
| FBN2 | fibrillin 2 |
| FMOD | fibromodulin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXO4 | forkhead box O4 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GOLGA4 | golgin A4 |
| GSN | gelsolin |
| H2AFY | H2A histone family, member Y |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IL17RB | interleukin 17 receptor B |
| MED1 | mediator complex subunit 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NOS3 | nitric oxide synthase 3 (endothelial cell) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| PCGF2 | polycomb group ring finger 2 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFRP1 | secreted frizzled-related protein 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| TFF3 | trefoil factor 3 (intestinal) |
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CD47 | CD47 molecule |
| CD52 | CD52 molecule |
| CDC42 | cell division cycle 42 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CYCS | cytochrome c, somatic |
| DHCR7 | 7-dehydrocholesterol reductase |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| GLIPR1 | GLI pathogenesis-related 1 |
| HAT1 | histone acetyltransferase 1 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| JAG1 | jagged 1 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LUM | lumican |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MSMO1 | methylsterol monooxygenase 1 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| SFN | stratifin |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| SQLE | squalene epoxidase |
| TFRC | transferrin receptor |
| TLR4 | toll-like receptor 4 |
| TMEM126B | transmembrane protein 126B |
| TSPAN8 | tetraspanin 8 |
| TXNDC9 | thioredoxin domain containing 9 |
