Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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77 genes differentially expressed following the BRD-K42436189_AZ20_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
COL11A1 | collagen, type XI, alpha 1 |
COMT | catechol-O-methyltransferase |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DICER1 | dicer 1, ribonuclease type III |
DLC1 | DLC1 Rho GTPase activating protein |
DLK1 | delta-like 1 homolog (Drosophila) |
GAL | galanin/GMAP prepropeptide |
GDF15 | growth differentiation factor 15 |
H1F0 | H1 histone family, member 0 |
H3F3B | H3 histone, family 3B (H3.3B) |
HIST1H1C | histone cluster 1, H1c |
HIST1H2BK | histone cluster 1, H2bk |
HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
IFI44L | interferon-induced protein 44-like |
IFI6 | interferon, alpha-inducible protein 6 |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
NMU | neuromedin U |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PROM1 | prominin 1 |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPS11 | ribosomal protein S11 |
RPS27L | ribosomal protein S27-like |
S100A14 | S100 calcium binding protein A14 |
SELL | selectin L |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SESN1 | sestrin 1 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SMAD1 | SMAD family member 1 |
STK10 | serine/threonine kinase 10 |
TNNT1 | troponin T type 1 (skeletal, slow) |
UBE3A | ubiquitin protein ligase E3A |
UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
VDAC1 | voltage-dependent anion channel 1 |
WNK1 | WNK lysine deficient protein kinase 1 |
Symbol | Name |
---|---|
ADGRG1 | adhesion G protein-coupled receptor G1 |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CAV2 | caveolin 2 |
CD24 | CD24 molecule |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CDK14 | cyclin-dependent kinase 14 |
CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
CISD1 | CDGSH iron sulfur domain 1 |
CLU | clusterin |
DMTF1 | cyclin D binding myb-like transcription factor 1 |
EPHA3 | EPH receptor A3 |
FGFR2 | fibroblast growth factor receptor 2 |
GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
GBP2 | guanylate binding protein 2, interferon-inducible |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
IL32 | interleukin 32 |
LRP2 | low density lipoprotein receptor-related protein 2 |
LTBP2 | latent transforming growth factor beta binding protein 2 |
LTF | lactotransferrin |
MMP12 | matrix metallopeptidase 12 |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NEFH | neurofilament, heavy polypeptide |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
NVL | nuclear VCP-like |
PGM1 | phosphoglucomutase 1 |
PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
RGCC | regulator of cell cycle |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
VLDLR | very low density lipoprotein receptor |
WFDC2 | WAP four-disulfide core domain 2 |
XIST | X inactive specific transcript (non-protein coding) |