| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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197 genes differentially expressed following the BRD-K42918627_GSK-2126458_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABLIM1 | actin binding LIM protein 1 |
| ADCK3 | aarF domain containing kinase 3 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AHR | aryl hydrocarbon receptor |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ANXA4 | annexin A4 |
| BTF3 | basic transcription factor 3 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CAMLG | calcium modulating ligand |
| CAPN3 | calpain 3, (p94) |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| COL8A2 | collagen, type VIII, alpha 2 |
| COMP | cartilage oligomeric matrix protein |
| CRISP3 | cysteine-rich secretory protein 3 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DALRD3 | DALR anticodon binding domain containing 3 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DST | dystonin |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| EIF3G | eukaryotic translation initiation factor 3, subunit G |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FOLR1 | folate receptor 1 (adult) |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HBP1 | HMG-box transcription factor 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGHM | immunoglobulin heavy constant mu |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| IRS2 | insulin receptor substrate 2 |
| LETMD1 | LETM1 domain containing 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LOC100272216 | uncharacterized LOC100272216 |
| LXN | latexin |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MTMR11 | myotubularin related protein 11 |
| MVP | major vault protein |
| MXI1 | MAX interactor 1, dimerization protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NELL2 | NEL-like 2 (chicken) |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| OPTN | optineurin |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
| PLCB4 | phospholipase C, beta 4 |
| PLS3 | plastin 3 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| QARS | glutaminyl-tRNA synthetase |
| RPL22 | ribosomal protein L22 |
| RPL28 | ribosomal protein L28 |
| RPL31 | ribosomal protein L31 |
| RPL36 | ribosomal protein L36 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RSRP1 | arginine/serine-rich protein 1 |
| SERINC3 | serine incorporator 3 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| SLC35E2B | solute carrier family 35, member E2B |
| SPATA20 | spermatogenesis associated 20 |
| SQSTM1 | sequestosome 1 |
| STX1A | syntaxin 1A (brain) |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
| THBD | thrombomodulin |
| TMEM63A | transmembrane protein 63A |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TSC22D1 | TSC22 domain family, member 1 |
| VAT1 | vesicle amine transport 1 |
| WDR45 | WD repeat domain 45 |
| YBX3 | Y box binding protein 3 |
| Symbol | Name |
|---|---|
| AK4 | adenylate kinase 4 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCNA2 | cyclin A2 |
| CCND3 | cyclin D3 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CSTA | cystatin A (stefin A) |
| DBF4 | DBF4 zinc finger |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF4E | eukaryotic translation initiation factor 4E |
| EIF5A | eukaryotic translation initiation factor 5A |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMNN | geminin, DNA replication inhibitor |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HIST1H4C | histone cluster 1, H4c |
| HMGB1 | high mobility group box 1 |
| HMGB2 | high mobility group box 2 |
| HSPA1A | heat shock 70kDa protein 1A |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT5 | keratin 5, type II |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LMNB2 | lamin B2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MKI67 | marker of proliferation Ki-67 |
| MT1X | metallothionein 1X |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OIP5 | Opa interacting protein 5 |
| PBK | PDZ binding kinase |
| PDHX | pyruvate dehydrogenase complex, component X |
| PIP | prolactin-induced protein |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAD51AP1 | RAD51 associated protein 1 |
| RAD51C | RAD51 paralog C |
| RBM38 | RNA binding motif protein 38 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RGS2 | regulator of G-protein signaling 2 |
| RRM2 | ribonucleotide reductase M2 |
| S100A9 | S100 calcium binding protein A9 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SELT | selenoprotein T |
| SEPHS1 | selenophosphate synthetase 1 |
| SESN1 | sestrin 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SMC2 | structural maintenance of chromosomes 2 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SRGN | serglycin |
| SRSF3 | serine/arginine-rich splicing factor 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STMN1 | stathmin 1 |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TF | transferrin |
| TIMELESS | timeless circadian clock |
| TK1 | thymidine kinase 1, soluble |
| TMPO | thymopoietin |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBG1 | tubulin, gamma 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VRK1 | vaccinia related kinase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
