| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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148 genes differentially expressed following the BRD-K42918627_GSK-2126458_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AGR2 | anterior gradient 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKRD36B | ankyrin repeat domain 36B |
| APOD | apolipoprotein D |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ATP9A | ATPase, class II, type 9A |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BEX4 | brain expressed, X-linked 4 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CRISP3 | cysteine-rich secretory protein 3 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DUSP1 | dual specificity phosphatase 1 |
| DYNLT3 | dynein, light chain, Tctex-type 3 |
| EDN1 | endothelin 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FOXO4 | forkhead box O4 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GATA2 | GATA binding protein 2 |
| GLS | glutaminase |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8H | golgin A8 family, member H |
| GPR137B | G protein-coupled receptor 137B |
| GSN | gelsolin |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBB | hemoglobin, beta |
| HLA-E | major histocompatibility complex, class I, E |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IDS | iduronate 2-sulfatase |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| LOC100272216 | uncharacterized LOC100272216 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAGEA3 | melanoma antigen family A3 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MOAP1 | modulator of apoptosis 1 |
| MVP | major vault protein |
| NBR1 | neighbor of BRCA1 gene 1 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 |
| NMRK1 | nicotinamide riboside kinase 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCB4 | phospholipase C, beta 4 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTEN | phosphatase and tensin homolog |
| RABAC1 | Rab acceptor 1 (prenylated) |
| RAP1GAP | RAP1 GTPase activating protein |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SNX11 | sorting nexin 11 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATA20 | spermatogenesis associated 20 |
| SYT17 | synaptotagmin XVII |
| TFF3 | trefoil factor 3 (intestinal) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOX3 | TOX high mobility group box family member 3 |
| TSPAN13 | tetraspanin 13 |
| TXNIP | thioredoxin interacting protein |
| VAT1 | vesicle amine transport 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIF1 | WNT inhibitory factor 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| APOA1 | apolipoprotein A-I |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CCNA2 | cyclin A2 |
| CDC20 | cell division cycle 20 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CEP57 | centrosomal protein 57kDa |
| CHEK2 | checkpoint kinase 2 |
| CPE | carboxypeptidase E |
| DBF4 | DBF4 zinc finger |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF5A | eukaryotic translation initiation factor 5A |
| EREG | epiregulin |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FEN1 | flap structure-specific endonuclease 1 |
| FKBP5 | FK506 binding protein 5 |
| FOSL1 | FOS-like antigen 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GGCT | gamma-glutamylcyclotransferase |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLIPR1 | GLI pathogenesis-related 1 |
| HAT1 | histone acetyltransferase 1 |
| HMGB2 | high mobility group box 2 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSPA14 | heat shock 70kDa protein 14 |
| HSPA4L | heat shock 70kDa protein 4-like |
| LBR | lamin B receptor |
| LMNB1 | lamin B1 |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MELK | maternal embryonic leucine zipper kinase |
| MMP12 | matrix metallopeptidase 12 |
| MMP9 | matrix metallopeptidase 9 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYBPC1 | myosin binding protein C, slow type |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NEK2 | NIMA-related kinase 2 |
| NUP85 | nucleoporin 85kDa |
| ODC1 | ornithine decarboxylase 1 |
| PBK | PDZ binding kinase |
| PON3 | paraoxonase 3 |
| PRC1 | protein regulator of cytokinesis 1 |
| RAB20 | RAB20, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RPIA | ribose 5-phosphate isomerase A |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| RTN1 | reticulon 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRM | spermidine synthase |
| TFRC | transferrin receptor |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
| ZWINT | ZW10 interacting kinetochore protein |
