| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
208 genes differentially expressed following the BRD-K42918627_GSK-2126458_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| AGR2 | anterior gradient 2 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| BPTF | bromodomain PHD finger transcription factor |
| C6ORF48 | chromosome 6 open reading frame 48 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CAMLG | calcium modulating ligand |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDK7 | cyclin-dependent kinase 7 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP57 | centrosomal protein 57kDa |
| CIRBP | cold inducible RNA binding protein |
| CLDN10 | claudin 10 |
| CST1 | cystatin SN |
| CYB5R1 | cytochrome b5 reductase 1 |
| DAPK1 | death-associated protein kinase 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DSG2 | desmoglein 2 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D |
| EIF4B | eukaryotic translation initiation factor 4B |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ESR1 | estrogen receptor 1 |
| FAM129A | family with sequence similarity 129, member A |
| FOXO3 | forkhead box O3 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GLUL | glutamate-ammonia ligase |
| GOLGB1 | golgin B1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HEBP1 | heme binding protein 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| KAT6B | K(lysine) acetyltransferase 6B |
| KIAA0355 | KIAA0355 |
| KIAA1033 | KIAA1033 |
| KIAA1324 | KIAA1324 |
| KIZ | kizuna centrosomal protein |
| KLHDC2 | kelch domain containing 2 |
| KLHL24 | kelch-like family member 24 |
| LCN2 | lipocalin 2 |
| LETMD1 | LETM1 domain containing 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LRRC1 | leucine rich repeat containing 1 |
| LXN | latexin |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MGLL | monoglyceride lipase |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MVP | major vault protein |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| OFD1 | oral-facial-digital syndrome 1 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PLSCR3 | phospholipid scramblase 3 |
| PLTP | phospholipid transfer protein |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| QARS | glutaminyl-tRNA synthetase |
| RAB9A | RAB9A, member RAS oncogene family |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS10 | regulator of G-protein signaling 10 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SECISBP2L | SECIS binding protein 2-like |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TMC5 | transmembrane channel-like 5 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) |
| TRIM2 | tripartite motif containing 2 |
| TUG1 | taurine up-regulated 1 (non-protein coding) |
| TXNIP | thioredoxin interacting protein |
| UBXN4 | UBX domain protein 4 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| USP9X | ubiquitin specific peptidase 9, X-linked |
| VNN1 | vanin 1 |
| WDR45 | WD repeat domain 45 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF277 | zinc finger protein 277 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| AURKA | aurora kinase A |
| BAG2 | BCL2-associated athanogene 2 |
| BCHE | butyrylcholinesterase |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CA2 | carbonic anhydrase II |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CCND2 | cyclin D2 |
| CD24 | CD24 molecule |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC42 | cell division cycle 42 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CEP55 | centrosomal protein 55kDa |
| CKB | creatine kinase, brain |
| CKLF | chemokine-like factor |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CTPS1 | CTP synthase 1 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYCS | cytochrome c, somatic |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DBF4 | DBF4 zinc finger |
| DCK | deoxycytidine kinase |
| DEPDC1 | DEP domain containing 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| E2F2 | E2F transcription factor 2 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAS | Fas cell surface death receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXM1 | forkhead box M1 |
| FRZB | frizzled-related protein |
| GAL | galanin/GMAP prepropeptide |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GNAS | GNAS complex locus |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HBB | hemoglobin, beta |
| HN1 | hematological and neurological expressed 1 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| HRASLS | HRAS-like suppressor |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IL1RN | interleukin 1 receptor antagonist |
| INSIG1 | insulin induced gene 1 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT5 | keratin 5, type II |
| LMNB2 | lamin B2 |
| LRRC59 | leucine rich repeat containing 59 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MALT1 | MALT1 paracaspase |
| MELK | maternal embryonic leucine zipper kinase |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYLK | myosin light chain kinase |
| NCAM1 | neural cell adhesion molecule 1 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NEK2 | NIMA-related kinase 2 |
| PBK | PDZ binding kinase |
| PCP4 | Purkinje cell protein 4 |
| PDE8B | phosphodiesterase 8B |
| PEG10 | paternally expressed 10 |
| PGAM1 | phosphoglycerate mutase 1 (brain) |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PNP | purine nucleoside phosphorylase |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRC1 | protein regulator of cytokinesis 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTTG1 | pituitary tumor-transforming 1 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RRM2 | ribonucleotide reductase M2 |
| S100A2 | S100 calcium binding protein A2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCG2 | secretogranin II |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC35B1 | solute carrier family 35, member B1 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SMC4 | structural maintenance of chromosomes 4 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TMEM45A | transmembrane protein 45A |
| TNC | tenascin C |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBA4A | tubulin, alpha 4a |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| WSB2 | WD repeat and SOCS box containing 2 |
| ZWINT | ZW10 interacting kinetochore protein |
