BRD-K43002773_GDC-0068_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K43002773_GDC-0068_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY1 adenylate cyclase 1 (brain)
ADIRF adipogenesis regulatory factor
ALB albumin
AQP3 aquaporin 3 (Gill blood group)
CCNG2 cyclin G2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CXADR coxsackie virus and adenovirus receptor
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH1 dimethylarginine dimethylaminohydrolase 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
GDF15 growth differentiation factor 15
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H2AC histone cluster 1, H2ac
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
MMP7 matrix metallopeptidase 7
MXI1 MAX interactor 1, dimerization protein
NELL2 NEL-like 2 (chicken)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX1 pre-B-cell leukemia homeobox 1
PCP4 Purkinje cell protein 4
PDZK1IP1 PDZK1 interacting protein 1
SASH1 SAM and SH3 domain containing 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMAD3 SMAD family member 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SVIL supervillin
TBC1D4 TBC1 domain family, member 4
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM7SF2 transmembrane 7 superfamily member 2
VCAN versican
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
C7 complement component 7
CD58 CD58 molecule
CLIC5 chloride intracellular channel 5
CSTA cystatin A (stefin A)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DLK1 delta-like 1 homolog (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5 eukaryotic translation initiation factor 5
F3 coagulation factor III (thromboplastin, tissue factor)
FABP7 fatty acid binding protein 7, brain
GAL galanin/GMAP prepropeptide
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GSTP1 glutathione S-transferase pi 1
ITGB1BP1 integrin beta 1 binding protein 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT10 keratin 10, type I
LMO4 LIM domain only 4
LTF lactotransferrin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PDZD2 PDZ domain containing 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCRG1 stimulator of chondrogenesis 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
TUBA4A tubulin, alpha 4a
VGLL4 vestigial-like family member 4
Funding