BRD-K43245338_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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115 genes differentially expressed following the BRD-K43245338_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANK2 ankyrin 2, neuronal
ANXA3 annexin A3
ANXA5 annexin A5
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BASP1 brain abundant, membrane attached signal protein 1
BICC1 BicC family RNA binding protein 1
BST2 bone marrow stromal cell antigen 2
C2CD2 C2 calcium-dependent domain containing 2
C5AR1 complement component 5a receptor 1
CCNE2 cyclin E2
CCPG1 cell cycle progression 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL5A2 collagen, type V, alpha 2
CPVL carboxypeptidase, vitellogenic-like
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTSS cathepsin S
DMXL2 Dmx-like 2
EGR3 early growth response 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ETV1 ets variant 1
F13A1 coagulation factor XIII, A1 polypeptide
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FBLN1 fibulin 1
FBP1 fructose-1,6-bisphosphatase 1
FBXL5 F-box and leucine-rich repeat protein 5
FGL2 fibrinogen-like 2
GSN gelsolin
HBD hemoglobin, delta
HEG1 heart development protein with EGF-like domains 1
HSPB8 heat shock 22kDa protein 8
INTS3 integrator complex subunit 3
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
LY75 lymphocyte antigen 75
MEIS1 Meis homeobox 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP7 matrix metallopeptidase 7
NBN nibrin
NR2F2 nuclear receptor subfamily 2, group F, member 2
OGFRL1 opioid growth factor receptor-like 1
PBX1 pre-B-cell leukemia homeobox 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
QKI QKI, KH domain containing, RNA binding
RBM47 RNA binding motif protein 47
RBPMS RNA binding protein with multiple splicing
RCN1 reticulocalbin 1, EF-hand calcium binding domain
S100P S100 calcium binding protein P
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STAT1 signal transducer and activator of transcription 1, 91kDa
SVIL supervillin
TLE4 transducin-like enhancer of split 4
TLR4 toll-like receptor 4
TMX4 thioredoxin-related transmembrane protein 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TUSC3 tumor suppressor candidate 3
TYMP thymidine phosphorylase
WDR19 WD repeat domain 19

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CDC42 cell division cycle 42
COL6A1 collagen, type VI, alpha 1
DNTT DNA nucleotidylexotransferase
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
FCGBP Fc fragment of IgG binding protein
FST follistatin
GPM6B glycoprotein M6B
GUSBP3 glucuronidase, beta pseudogene 3
HP haptoglobin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IPO13 importin 13
ITGA6 integrin, alpha 6
KLHL24 kelch-like family member 24
KRT5 keratin 5, type II
MT1E metallothionein 1E
MUC2 mucin 2, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OXA1L oxidase (cytochrome c) assembly 1-like
PAX5 paired box 5
PLK1 polo-like kinase 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRO protein tyrosine phosphatase, receptor type, O
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8
STEAP1 six transmembrane epithelial antigen of the prostate 1
TF transferrin
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
VEGFA vascular endothelial growth factor A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91