Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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214 genes differentially expressed following the BRD-K43389698_BMS-387032_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AAMDC | adipogenesis associated, Mth938 domain containing |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
ALB | albumin |
ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
ALG8 | ALG8, alpha-1,3-glucosyltransferase |
AMBP | alpha-1-microglobulin/bikunin precursor |
ANKRD36B | ankyrin repeat domain 36B |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ASPN | asporin |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
BCL2L1 | BCL2-like 1 |
C5AR1 | complement component 5a receptor 1 |
CCL20 | chemokine (C-C motif) ligand 20 |
CERS6 | ceramide synthase 6 |
CFB | complement factor B |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHL1 | cell adhesion molecule L1-like |
CLEC7A | C-type lectin domain family 7, member A |
COL11A1 | collagen, type XI, alpha 1 |
CPD | carboxypeptidase D |
CPE | carboxypeptidase E |
CTGF | connective tissue growth factor |
CTTN | cortactin |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYBB | cytochrome b-245, beta polypeptide |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
DMXL2 | Dmx-like 2 |
DUSP2 | dual specificity phosphatase 2 |
EGR1 | early growth response 1 |
ENO2 | enolase 2 (gamma, neuronal) |
EREG | epiregulin |
F12 | coagulation factor XII (Hageman factor) |
FAM13A | family with sequence similarity 13, member A |
FAM172A | family with sequence similarity 172, member A |
FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
FOXO4 | forkhead box O4 |
FRY | furry homolog (Drosophila) |
FST | follistatin |
GAGE3 | G antigen 3 |
GC | group-specific component (vitamin D binding protein) |
GLUL | glutamate-ammonia ligase |
GOLGA8A | golgin A8 family, member A |
GOLGA8B | golgin A8 family, member B |
GPM6A | glycoprotein M6A |
GSAP | gamma-secretase activating protein |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
HIST1H1C | histone cluster 1, H1c |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HP | haptoglobin |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IFRD2 | interferon-related developmental regulator 2 |
IGFBP3 | insulin-like growth factor binding protein 3 |
LTBP1 | latent transforming growth factor beta binding protein 1 |
LYN | LYN proto-oncogene, Src family tyrosine kinase |
LYZ | lysozyme |
MDFIC | MyoD family inhibitor domain containing |
MXRA7 | matrix-remodelling associated 7 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NELL2 | NEL-like 2 (chicken) |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
ORM1 | orosomucoid 1 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PRKCB | protein kinase C, beta |
PTN | pleiotrophin |
RBP4 | retinol binding protein 4, plasma |
RELN | reelin |
SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
SATB2 | SATB homeobox 2 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SDC2 | syndecan 2 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SMYD2 | SET and MYND domain containing 2 |
SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) |
SRPR | signal recognition particle receptor (docking protein) |
STC1 | stanniocalcin 1 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
STK10 | serine/threonine kinase 10 |
STK38L | serine/threonine kinase 38 like |
SULF1 | sulfatase 1 |
SYBU | syntabulin (syntaxin-interacting) |
TF | transferrin |
TGFB1 | transforming growth factor, beta 1 |
TGOLN2 | trans-golgi network protein 2 |
THBS1 | thrombospondin 1 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TM7SF2 | transmembrane 7 superfamily member 2 |
TMEM259 | transmembrane protein 259 |
TPP1 | tripeptidyl peptidase I |
TRA2A | transformer 2 alpha homolog (Drosophila) |
TSPAN7 | tetraspanin 7 |
TYROBP | TYRO protein tyrosine kinase binding protein |
VEGFA | vascular endothelial growth factor A |
Symbol | Name |
---|---|
ADGRG6 | adhesion G protein-coupled receptor G6 |
AGTR1 | angiotensin II receptor, type 1 |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
ARHGAP29 | Rho GTPase activating protein 29 |
ARID4B | AT rich interactive domain 4B (RBP1-like) |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
ATMIN | ATM interactor |
AURKA | aurora kinase A |
BASP1 | brain abundant, membrane attached signal protein 1 |
BLCAP | bladder cancer associated protein |
CBR3 | carbonyl reductase 3 |
CCNA2 | cyclin A2 |
CCNB2 | cyclin B2 |
CCNF | cyclin F |
CD24 | CD24 molecule |
CDC20 | cell division cycle 20 |
CDC25B | cell division cycle 25B |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CDH3 | cadherin 3, type 1, P-cadherin (placental) |
CENPA | centromere protein A |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CLTA | clathrin, light chain A |
COA3 | cytochrome c oxidase assembly factor 3 |
COTL1 | coactosin-like F-actin binding protein 1 |
CSE1L | CSE1 chromosome segregation 1-like (yeast) |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DLK1 | delta-like 1 homolog (Drosophila) |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EFHD1 | EF-hand domain family, member D1 |
ELF5 | E74-like factor 5 (ets domain transcription factor) |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FGFR2 | fibroblast growth factor receptor 2 |
FZD7 | frizzled class receptor 7 |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
GATA3 | GATA binding protein 3 |
GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
H2AFX | H2A histone family, member X |
H2AFZ | H2A histone family, member Z |
HMOX1 | heme oxygenase 1 |
HOXC6 | homeobox C6 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA8 | heat shock 70kDa protein 8 |
IGFBP6 | insulin-like growth factor binding protein 6 |
IGSF3 | immunoglobulin superfamily, member 3 |
JUP | junction plakoglobin |
KARS | lysyl-tRNA synthetase |
KAZN | kazrin, periplakin interacting protein |
KLK5 | kallikrein-related peptidase 5 |
KRT14 | keratin 14, type I |
KRT15 | keratin 15, type I |
KRT17 | keratin 17, type I |
KRT7 | keratin 7, type II |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LIMA1 | LIM domain and actin binding 1 |
LPAR1 | lysophosphatidic acid receptor 1 |
MALL | mal, T-cell differentiation protein-like |
MELK | maternal embryonic leucine zipper kinase |
MMP7 | matrix metallopeptidase 7 |
MSMB | microseminoprotein, beta- |
MYO1E | myosin IE |
MYOF | myoferlin |
NET1 | neuroepithelial cell transforming 1 |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
NUP62 | nucleoporin 62kDa |
PCNA | proliferating cell nuclear antigen |
PLK1 | polo-like kinase 1 |
PPAP2B | phosphatidic acid phosphatase type 2B |
PROM1 | prominin 1 |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
PUF60 | poly-U binding splicing factor 60KDa |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RAE1 | ribonucleic acid export 1 |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RNPS1 | RNA binding protein S1, serine-rich domain |
S100A6 | S100 calcium binding protein A6 |
S100A7 | S100 calcium binding protein A7 |
SLPI | secretory leukocyte peptidase inhibitor |
SOBP | sine oculis binding protein homolog (Drosophila) |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SQSTM1 | sequestosome 1 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
TLE4 | transducin-like enhancer of split 4 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TRAPPC3 | trafficking protein particle complex 3 |
TRIM29 | tripartite motif containing 29 |
TUBB3 | tubulin, beta 3 class III |
TUBB4B | tubulin, beta 4B class IVb |
TXLNA | taxilin alpha |
TXNRD1 | thioredoxin reductase 1 |
U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
UBE2C | ubiquitin-conjugating enzyme E2C |
USP22 | ubiquitin specific peptidase 22 |
VCP | valosin containing protein |
VGLL1 | vestigial-like family member 1 |
WDR82 | WD repeat domain 82 |